Results 51 to 60 of about 2,821,697 (256)

Prognostic and Remaining Life Prediction of Electronic Device under Vibration Condition Based on CPSD of MPI

open access: yesShock and Vibration, 2016
Prognostic of electronic device under vibration condition can help to get information to assist in condition-based maintenance and reduce life-cycle cost.
Ying Chen, Ning Tang, Zenghui Yuan
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An Integral Formulation of Two-Parameter Fatigue Crack Growth Model

open access: yesAdvances in Materials Science and Engineering, 2018
A two-parameter fatigue crack growth algorithm in integral form is proposed, which can describe the continuous crack growth process over the time period.
Jianguo Wu   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A reliability model for dependent and distributed MDS disk array units

open access: yes, 2018
Archiving and systematic backup of large digital data generates a quick demand for multi-petabyte scale storage systems. As drive capacities continue to grow beyond the few terabytes range to address the demands of today’s cloud, the likelihood of having
Arslan, Suayb S., Arslan, Şuayb Şefik
core   +1 more source

Skill Vehicle Routing Problem With Time Windows Considering Dynamic Service Times and Time-Skill-Dependent Costs

open access: yesIEEE Access, 2019
Service processes in modern logistic systems tend to be highly specialized and intellectualized. However, some casual and unexpected behavior may occur, causing specific dynamic interactions among their many constituents.
Xiaoyuan Yan   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Temperature Compensation of FBG Sensor for Monitoring the Stress on Hole-Edge

open access: yesIEEE Photonics Journal, 2018
To apply Fiber Bragg Grating (FBG) sensors in the hole structural health monitoring of aircraft, this study investigates a temperature compensation algorithm based on Fourier curve-fitting, combined with an analysis of FBG layout.
Feifei Ren   +5 more
doaj   +1 more source

Analysis of University Students’ Behavior Based on a Fusion K-Means Clustering Algorithm

open access: yesApplied Sciences, 2020
With the development of big data technology, creating the ‘Digital Campus’ is a hot issue. For an increasing amount of data, traditional data mining algorithms are not suitable. The clustering algorithm is becoming more and more important in the field of
Wenbing Chang   +6 more
doaj   +1 more source

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