Results 141 to 150 of about 4,331,943 (376)

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Reliability physics [PDF]

open access: yes
Speakers whose topics relate to the reliability physics of solar arrays are listed and their topics briefly reviewed. Nine reports are reviewed ranging in subjects from studies of photothermal degradation in encapsulants and polymerizable ultraviolet ...
Cuddihy, E. F., Ross, R. G., Jr.
core   +1 more source

Design reliability goal developed from small sample [PDF]

open access: yes, 1966
Sampling distributions, constructed by Monte Carlo simulation are used in hardware development to establish a design reliability goal, to place a confidence coefficient on reliability estimates, and to determine whether sample stress/strength data ...
Burrows, D. L., Heathcock, R.
core   +1 more source

DeSyRe: on-Demand System Reliability

open access: yes, 2013
The DeSyRe project builds on-demand adaptive and reliable Systems-on-Chips (SoCs). As fabrication technology scales down, chips are becoming less reliable, thereby incurring increased power and performance costs for fault tolerance. To make matters worse,
Armato, Antonino   +17 more
core   +1 more source

Reliability: an introduction [PDF]

open access: yesSynthese, 2020
Bonzio S., Landes J., Osimani B.
openaire   +2 more sources

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Reliability Estimation of News Media Sources: Birds of a Feather Flock Together [PDF]

open access: yes
Evaluating the reliability of news sources is a routine task for journalists and organizations committed to acquiring and disseminating accurate information. Recent research has shown that predicting sources' reliability represents an important first-prior step in addressing additional challenges such as fake news detection and fact-checking.
arxiv   +1 more source

Conditional Reliability in Uncertain Graphs

open access: yes, 2018
Network reliability is a well-studied problem that requires to measure the probability that a target node is reachable from a source node in a probabilistic (or uncertain) graph, i.e., a graph where every edge is assigned a probability of existence. Many
Bonchi, Francesco   +3 more
core   +1 more source

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