Results 151 to 160 of about 4,331,943 (376)
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
Internal reliability and anti-reliability in dynamical networks [PDF]
arXivWe consider finite dynamical networks and define internal reliability according to the synchronization properties of a replicated unit or a set of units. If the states of the replicated units coincide with their prototypes, they are reliable; otherwise, if their states differ, they are anti-reliable.
arxiv
Iterative LDPC decoding using neighborhood reliabilities [PDF]
arXiv, 2007 In this paper we study the impact of the processing order of nodes of a bipartite graph, on the performance of an iterative message-passing decoding. To this end, we introduce the concept of neighborhood reliabilities of graph's nodes. Nodes reliabilities are calculated at each iteration and then are used to obtain a processing order within a serial or
arxiv
Scientific ReportsThe sensor that simultaneously perceives bending strain and magnetic field has the potential to detect the finger bending state and hand position of the human and robot.
Qian Wang +5 more
doaj +1 more source
The reliability problem for reliabilism [PDF]
, 2018 According to process reliabilism, a belief produced by a reliable belief-forming process is justified. I introduce problems for this theory on any account of reliability.
Frise, Matthew
core
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
Higher-Order Meta Distribution Analysis of Wireless Systems with Application to the Reliability of UWB THz Networks [PDF]
arXivCommunication reliability, as defined by 3GPP, refers to the probability of providing a desired quality of service (QoS). This metric is typically quantified for wireless networks by averaging the QoS success indicator over spatial and temporal random variables.
arxiv