ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Using Large Language Models for In Silico Development and Simulation of a Patient-Reported Outcome Questionnaire for Cataract Surgery with Various Intraocular Lenses: A Pre-Validation Study. [PDF]
Trojacka E +6 more
europepmc +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Validity and reliability testing of the Pelvic Pain Impact Questionnaire. [PDF]
Kovács-Szabó Z +3 more
europepmc +1 more source
Investigation of MOSFET Transistor Reliability under Pulsed-RF Life Tests
Ahmed Almusallam, M.A. Belaïd
openalex +1 more source
Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda +12 more
wiley +1 more source
Development of Health Enhancement Lifestyle Profile - Taiwanese Short Form Version (HELP-T-SF) for the community-dwelling elderly. [PDF]
Su PC, Mao HF, Cheng WC.
europepmc +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Reducing patient burden of PROMs in healthcare through advanced computerized adaptive testing stopping rules. [PDF]
Luijten MAJ +4 more
europepmc +1 more source

