Results 111 to 120 of about 7,446,052 (296)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Beyond Accuracy: Reliability-Aware Machine Learning for Handwriting-Based Alzheimer’s Disease Detection

open access: yesInformation
Reliable clinical decision support systems require not only high predictive accuracy but also trustworthy probability estimates and robust uncertainty quantification.
Uddalak Mitra, Shafiq Ul Rehman
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Identifying the intended user(s) and use(s) of an evaluation [PDF]

open access: yes, 2012
French version available in IDRC Digital Library: Détermination des utilisateurs et des utilisations prévus d’une évaluationThe decision to evaluate should be strategic and not rote.
IDRC. Evaluation Unit
core   +1 more source

Operational Reliability Assessment in Power Systems Considering Frequency Regulation of Virtual Power Plants

open access: yesIEEE Access
Virtual power plants (VPPs), as aggregations of demand-side flexible resources, can provide peak-shaving and frequency-regulation services. However, the coupling between aggregated VPP frequency support and generation-side operational reliability has not
Bo Fu, Yingdan Wang, Shuyi Fan
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Reliability analysis of soil-rock composite slopes based on dimensionality reduction response surface method

open access: yesFrontiers in Materials
To address the “curse of dimensionality” caused by high-dimensional parameters and the computational bottlenecks of 3D numerical simulations in the reliability evaluation of “overlying silty clay and underlying weathered mylonite” composite strata slopes,
Libiao Feng   +11 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Reliable Evaluation of Multimodal Dialogue Systems

open access: yes, 2009
Usability evaluation is an indispensable issue during the development of new interfaces and interaction paradigms [1]. Although a wide range of reliable usability evaluation methods exists for graphical user interfaces, mature methods are rarely available for speech-based interfaces [2].
Florian Metze   +4 more
openaire   +2 more sources

A Modified Universal Generating Function Algorithm For The Acyclic Binary-State Network Reliability

open access: yes, 2012
Network reliability is an important part of planning, designing, and controlling networks. Now, the most general binary-state network (BSN) reliability evaluation methods are based on Minimal Paths (MPs), or Minimal Cuts (MCs). The universal generating
Yeh, W
core   +1 more source

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