Results 101 to 110 of about 18,162,333 (306)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Service reliability evaluation of highway tunnel based on digital image processing. [PDF]
Dai C +5 more
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Composite system reliability evaluation
Abstract At present there is a significant interest in composite generation and transmission system reliability evaluation for use in bulk power system planning. Methods and computer programs for composite system reliability evaluation have been reported in the industry, though their applications in electric utilities are still very limited.
openaire +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Tool holders are one of the most important structures in transferring machine tools and energy for manufacturing in CNC lathe. Power servo tool holders influence kinematic accuracy and machining accuracy and so are vital to the transposition system ...
Di Zhou +4 more
doaj +1 more source
Reliability Evaluation of GaAsFETS. [PDF]
Abstract : The objective of this program was to assess and establish the reliability and life characteristics of commercially available, medium power GaAs MESFETs and to identify any associated failure mechanisms. The devices chosen for this study were the TI MSX802 and laboratory devices and devices from three other manufacturers, A, B, and C.
openaire +1 more source
DNN based reliability evaluation for telemedicine data. [PDF]
Shin DA, Kim J, Choi SW, Lee JC.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source

