Results 81 to 90 of about 18,162,333 (306)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Validation of Land Cover Products Using Reliability Evaluation Methods
Remote Sensing, 2015 Validation of land cover products is a fundamental task prior to data applications. Current validation schemes and methods are, however, suited only for assessing classification accuracy and disregard the reliability of land cover products.
Wenzhong Shi +5 more
doaj +1 more source
Reliability evaluation of electricity-heat integrated energy system with heat pump
CSEE Journal of Power and Energy Systems, 2018 Integrated energy system (IES) has the advantages of improving the efficiency of energy utilization and promoting the consumption of renewable energy. It is of great importance to evaluate the reliability of an IES.
Shenxi Zhang +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A convolutional neural network-based approach to composite power system reliability evaluation
, 2022 M. Kamruzzaman +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A new method for computing the reliability of consecutive k-out-of-n:F systems
Open Physics, 2016 In many physical systems, reliability evaluation, such as ones encountered in telecommunications, the design of integrated circuits, microwave relay stations, oil pipeline systems, vacuum systems in accelerators, computer ring networks, and spacecraft ...
Gökdere Gökhan +2 more
doaj +1 more source
Reliable Evaluation of Adversarial Transferability
2025 IEEE Conference on Secure and Trustworthy Machine Learning (SaTML)Adversarial examples (AEs) with small adversarial perturbations can mislead deep neural networks (DNNs) into wrong predictions. The AEs created on one DNN can also fool another DNN. Over the last few years, the transferability of AEs has garnered significant attention as it is a crucial property for facilitating black-box attacks.
Yu, W, Gu, J, Li, Z, Torr, P
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source