Results 81 to 90 of about 7,446,052 (296)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A Layered Fault Tree Model for Reliability Evaluation of Smart Grids

open access: yesEnergies, 2014
The smart grid concept has emerged as a result of the requirement for renewable energy resources and application of new techniques. It is proposed as a practical future form of power distribution system.
Guopeng Song, Hao Chen, Bo Guo
doaj   +1 more source

Evaluation of Reliability and Validity of the Çapa Anxiety Scale [PDF]

open access: yes, 2011
Aim:The aim of this study is to assess the reliability and validity of Çapa Anxiety Scale that is developed at Istanbul University Faculty of Dentistry Department of Orthodontics.Subjects and Methods:The study is carried out on two groups, aged between 8-
Hülya Kılıçoğlu   +2 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Weighted averaging fusion for multi‐view skeletal data and its application in action recognition

open access: yesIET Computer Vision, 2016
Existing studies in skeleton‐based action recognition mainly utilise skeletal data taken from a single camera. Since the quality of skeletal tracking of a single camera is noisy and unreliable, however, combining data from multiple cameras can improve ...
Nur Aziza Azis   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Analytical evaluation method of reliability considering interaction between transmission network and flexible interconnected distribution network

open access: yes电力工程技术
When applying the fault enumeration method to evaluate the reliability of the whole transmission and distribution network composed of transmission network and flexible interconnected distribution network, apart from analyzing the influence of internal ...
SHI Mingming   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Multi-Objective Optimization and Reliability Assessment of Multi-Layer Radiation Shielding for Deep Space Missions

open access: yesAerospace
This study proposes an advanced space radiation shielding design method that integrates multi-objective optimization with reliability evaluation to mitigate the impact of harsh space radiation environments on electronic systems.
Shukai Guan   +4 more
doaj   +1 more source

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