Results 71 to 80 of about 2,268,235 (274)

Multivariate reliability modelling with empirical Bayes inference [PDF]

open access: yes, 2007
Recent developments in technology permit detailed descriptions of system performance to be collected and stored. Consequently, more data are available about the occurrence, or non-occurrence, of events across a range of classes through time.
Quigley, J.L., Walls, L.A.
core  

Extremality for Gallager’s Reliability Function $E_{0}$ [PDF]

open access: yesIEEE Transactions on Information Theory, 2015
39 pages, submitted to IEEE Transactions on Information ...
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Robust Dynamic Selection of Tested Modules in Software Testing for Maximizing Delivered Reliability [PDF]

open access: yes, 2017
Software testing is aimed to improve the delivered reliability of the users. Delivered reliability is the reliability of using the software after it is delivered to the users. Usually the software consists of many modules. Thus, the delivered reliability
Cai, Kai-Yuan   +3 more
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

An optimal scale for the comparison of air pollution in east and west Tehran [PDF]

open access: yesعلوم محیطی, 2018
Introduction: Air pollution in the metropolis of Tehran is a serious environmental issue. Assigning an optimal budget to deal with air pollution problems in the East (no.4) and West (no.22) regions of Tehran, determining the optimal proportion of green ...
Masoud Ganji, Akbar Abravesh
doaj  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Optimization of structures on the basis of fracture mechanics and reliability criteria [PDF]

open access: yes, 1973
Systematic summary of factors which are involved in optimization of given structural configuration is part of report resulting from study of analysis of objective function.
Heer, E., Yang, J. N.
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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