Results 61 to 70 of about 770,998 (218)
Giving Hope as a High Reliability Function of Health Care. [PDF]
J Patient Exp, 2023 Mylod D, Lee TH.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015 В роботі здійснено розрахунок ймовірності безвідмовної роботи послідовно з’єднаних і резервованих елементів без відновлення для дифузійно–немонотонного (ДН) розподілу їх відмов. Розрахунки здійснені для виробів електронного типу.
Volodymyr I. Mirnenko +2 more
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
One Parameter Polynomial Exponential Distribution with Binomial Mixture
Revstat Statistical JournalA further generalized version of one parameter polynomial exponential distribution with binomial probability mass as a mixture called a Binomial Mixture One Parameter Polynomial Exponential Distribution (BMOPPE) is proposed in the article.
Molay Kumar Ruidas +4 more
doaj +1 more source
A Software Reliability Model Using Quantile Function
Journal of Probability and Statistics, 2014 We study a class of software reliability models using quantile function. Various distributional properties of the class of distributions are studied. We also discuss the reliability characteristics of the class of distributions.
Bijamma Thomas +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source