Results 41 to 50 of about 770,998 (218)

Maximum Penalized Likelihood Estimation for the Reliability Function [PDF]

open access: yesThe Egyptian Statistical Journal, 2016
This paper considers the problem of estimating probability density function based on maximum   Maximum Penalized Likelihood Estimation , we will review some of the previous studies on  Maximum Penalized Likelihood Estimation  ( MPLE) approaches. Finally,
A. Mousa, M. khalil, N. Said, A. Fathi
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Boltzmann-like Entropy in Reliability Theory

open access: yesEntropy, 2002
: We introduce the entropy function in order to study the reliability and repairability of systems. In detail we establish the explicit relationships between reliability and repairability; then we calculate the decay of a system due to its regular ...
Paolo Rocchi
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Stochastic Vibration of Damaged Cable System Under Random Loads

open access: yesVibration
This study proposes an integrated framework that combines nonlinear stochastic vibration analysis with reliability assessment to address the safety issues of cable systems under damage conditions.
Yihao Wang, Wei Li, Drazan Kozak
doaj   +1 more source

A reliability model for a wafer FAB

open access: yesCogent Engineering, 2017
Proposed in this paper is a new reliability model for a wafer fabrication plant (FAB). The reliability prediction of a FAB is essential for various activities; feasibility evaluation, comparing competing designs, identifying potential reliability ...
Joong S. Jang, Sang C. Park
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Estimation of the Reliability Function of the Generalized Rayleigh Distribution under Progressive First-Failure Censoring Model

open access: yesAxioms
This study investigates the statistical inference of the parameters, reliability function, and hazard function of the generalized Rayleigh distribution under progressive first-failure censoring samples, considering factors such as long product lifetime ...
Qin Gong   +3 more
doaj   +1 more source

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