Results 41 to 50 of about 720,222 (218)

Calculations of System Aging through the Stochastic Entropy

Entropy, 2006
The present research discusses four ‘physical’ models of system and calculates thereliability function during system’s aging and maturity on the basis of the system structure.
Paolo Rocchi
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Predicting Interval of Product Reliability With Bootsrap Percentile Method

Jurnal Ilmu Dasar, 2010
In this article, two methods are proposed to give the interval estimation for reliability function from a product. Reliability function is a probability of an individual (product) surviving till time t.
Akhmad Fauzy, Epha Diana Supandi
doaj  

Estimation of the two-parameter Weibull distribution parameters using the coefficient of variation

Vojnotehnički Glasnik, 1996
This paper presents a method for estimating the reliability function parameters when reliability function is the 2-parametar Weibull regression. This model is often used in a reliability analysis in wide variety of situations to approximate successfully ...
Slavko Tomović
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

An optimal scale for the comparison of air pollution in east and west Tehran [PDF]

علوم محیطی, 2018
Introduction: Air pollution in the metropolis of Tehran is a serious environmental issue. Assigning an optimal budget to deal with air pollution problems in the East (no.4) and West (no.22) regions of Tehran, determining the optimal proportion of green ...
Masoud Ganji, Akbar Abravesh
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Probabilistic Approach for Threshold Reliability Structures with Three Different Types of Components

Mathematics
In the present work, we study threshold reliability systems consisting of three different kinds of independent components. Within these structures, the components belonging to the same type, share a common reliability and the same weight. The reliability
Ioannis S. Triantafyllou
doaj   +1 more source