Results 21 to 30 of about 720,222 (218)

Parameter Reliability and Understanding Enzyme Function

Molecules, 2022
Knowledge of the Michaelis–Menten parameters and their meaning in different circumstances is an essential prerequisite to understanding enzyme function and behaviour. The published literature contains an abundance of values reported for many enzymes. The
Andrew G. McDonald, Keith F. Tipton
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

On the Reliability Function of Variable-Rate Slepian-Wolf Coding

Entropy, 2017
The reliability function of variable-rate Slepian-Wolf coding is linked to the reliability function of channel coding with constant composition codes, through which computable lower and upper bounds are derived.
Jun Chen, Da-ke He, Ashish Jagmohan, Luis A. Lastras-Montaño   +3 more
doaj   +1 more source

Shrinkage Estimators for Reliability Function [PDF]

مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2012
A variety of shrinkage methods for estimating unknown parameters has been considered. We derive and compare the shrinkage estimators for the reliability function of the two-parameter exponential distribution.
Mohammad Qabaha
doaj   +1 more source

Reliability-Aware Service Function Chain Backup Protection Method

IEEE Access, 2021
Network Function Virtualization (NFV) decouples network functions from hardware, improves the flexibility of resource allocation, and enhances network scalability.
Dong Zhai, Xiangru Meng, Zhenhua Yu, Xiaoyang Han   +3 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The Method of Types for the AWGN Channel

Entropy
For the discrete-time AWGN channel with a power constraint, we give an alternative derivation for the sphere-packing upper bound on the optimal block error exponent and an alternative derivation for the analogous lower bound on the optimal correct ...
Sergey Tridenski, Anelia Somekh-Baruch
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Reliability Estimation for Burr XII Distribution under the Weighted Q-Symmetric Entropy Loss Function

Applied Sciences
Considering that the choice of loss function plays a significant role in the derivation of Bayesian estimators, we propose a novel asymmetric loss function named the weighted Q-symmetric entropy loss for computing the estimates of the parameter and ...
Kexin He, Wenhao Gui
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source