Results 31 to 40 of about 720,222 (218)

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

One Parameter Polynomial Exponential Distribution with Binomial Mixture

Revstat Statistical Journal
A further generalized version of one parameter polynomial exponential distribution with binomial probability mass as a mixture called a Binomial Mixture One Parameter Polynomial Exponential Distribution (BMOPPE) is proposed in the article.
Molay Kumar Ruidas, Indrani Mukherjee, Mriganka Mouli Choudhury, Sudhansu S. Maiti , Sumanta Adhya   +4 more
doaj   +1 more source

Fuzzy Reliability Theory Based on Membership Function [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2016
In this study, it is considered that the shape of membership function and the values of parameters are arbitrary, hence reliability parameters will be arbitrary, and some data are even absurd from the point of view of real life practice. An applied fuzzy
Shshank Chaube, S. B. Singh
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring the Differential Geometry of Reliability Function: Insights from Lifetime Weibull Distributions Under Neutrosophic Environment [PDF]

Neutrosophic Sets and Systems
This paper characterizes a set N as a two-dimensional surface marked by 𝑅 + × 𝑅 + and demonstrates its properties as a topological 2-reliability manifold and a differential reliability manifold.
Nada Mohammed Abbas, Ghazi Abdullah, Ahmed Hadi Hussain   +2 more
doaj   +1 more source

Maximum Penalized Likelihood Estimation for the Reliability Function [PDF]

The Egyptian Statistical Journal, 2016
This paper considers the problem of estimating probability density function based on maximum   Maximum Penalized Likelihood Estimation , we will review some of the previous studies on  Maximum Penalized Likelihood Estimation  ( MPLE) approaches. Finally,
A. Mousa, M. khalil, N. Said, A. Fathi
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source