Results 71 to 80 of about 2,407,909 (292)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Probabilistic Approach for Threshold Reliability Structures with Three Different Types of Components

open access: yesMathematics
In the present work, we study threshold reliability systems consisting of three different kinds of independent components. Within these structures, the components belonging to the same type, share a common reliability and the same weight. The reliability
Ioannis S. Triantafyllou
doaj   +1 more source

Robust Dynamic Selection of Tested Modules in Software Testing for Maximizing Delivered Reliability [PDF]

open access: yes, 2017
Software testing is aimed to improve the delivered reliability of the users. Delivered reliability is the reliability of using the software after it is delivered to the users. Usually the software consists of many modules. Thus, the delivered reliability
Cai, Kai-Yuan   +3 more
core  

On the Reliability of Cross Correlation Function Lag Determinations in Active Galactic Nuclei

open access: yes, 1999
Many AGN exhibit a highly variable luminosity. Some AGN also show a pronounced time delay between variations seen in their optical continuum and in their emission lines. In effect, the emission lines are light echoes of the continuum.
Diaconis P.   +13 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Reliability and Its Quantitative Measures [PDF]

open access: yes
In this article is made an opening for the software reliability issues, through wide-ranging statistical indicators, which are designed based on information collected from operating or testing (samples).
Alexandru ISAIC-MANIU
core  

Parameter Estimates of General Failure Rate Model: A Bayesian Approach [PDF]

open access: yes, 2014
The failure rate function plays an important role in studying the lifetime distributions in reliability theory and life testing models. A study of the general failure rate model $r(t)=a+bt^{\theta-1}$, under squared error loss function taking $a$ and $b$
Kundu, Amarjit   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Assessing the Reliability Function of Nanocomponents [PDF]

open access: yesJournal of Applied Probability, 2011
A nanocomponent is a collection of atoms arranged to a specific design in order to achieve a desired function with an acceptable performance and reliability. The type of atoms, the manner in which they are arranged within the nanocomponent, and their interrelationship have a direct effect on the nanocomponent's reliability (survival) function.
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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