Results 71 to 80 of about 2,819,689 (302)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Quality Assurance Indicators of Long-Term Care in European Countries. ENEPRI Research Report No. 110, April 2012 [PDF]

open access: yes, 2012
This study reports on the quality indicators that were collected by the ANCIEN project partners in each country considered in Work Package 5 (Quality in Long-Term Care).
Casanova, Georgia, Dandi, Roberto
core  

Reliability and validity indicators of the constructs.

open access: yes, 2023
Reliability and validity indicators of the constructs.
Wai Mar Phyo (17696578)   +2 more
core   +1 more source

Temporal Network Reliability in Perturbed Scenarios: Application to a SCADA System

open access: yes, 2012
The role of network reliability in the analysis of Critical Infrastructures (CI) is investigated showing that the traditional approach must be extended in two directions: to include the packet propagation time along the links for real time analysis, and ...
Bonaventura, Alessandro   +15 more
core   +1 more source

Reliability and Its Quantitative Measures [PDF]

open access: yes
In this article is made an opening for the software reliability issues, through wide-ranging statistical indicators, which are designed based on information collected from operating or testing (samples).
Alexandru ISAIC-MANIU
core  

ANALYSIS OF INDICATORS OF RELIABILITY OF ELECTRICAL NETWORKS

open access: yesProblems of the Regional Energetics, 2012
Problems of the optimization reliability in electrical networks of the different class of voltage have probabilistic nature, they discretely change and depend on the number of factors both definite and indefinite and have importance by selection of ...
Popescu V.
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Assessment of the motor vehicle reliability key indicators

open access: yesTrudy Odesskogo Politehničeskogo Universiteta, 2015
Considered is a problem of longevity estimation and guaranteeing the preplanned lifespan of the automobile’s parts, assemblies and structural units.
Valery G. Maksimov   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy