Results 81 to 90 of about 2,819,689 (302)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Effects of reliability indicators on usage, acceptance and preference of predictive process management decision support systems. [PDF]

open access: yesQual User Exp, 2022
Fröhlich P   +6 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

On the reliability of quasars as cosmological distance indicators

open access: yesMonthly Notices of the Royal Astronomical Society
ABSTRACT We assess the viability of quasars as cosmological distance indicators based on the non-linear $L_X$–$L_{\rm UV}$ relation. We calibrate this relation in a model-independent way by anchoring quasar luminosity distances to cosmic-chronometer $H(z)$ measurements over $z\le 1.43$, and construct a quasar Hubble diagram extending ...
Ariadna Montiel   +3 more
openaire   +2 more sources

Quality Indicators Increase the Reliability of Microarray Data

open access: yesGenomics, 2002
Large-scale gene expression profiling with DNA microarrays opens new dimensions to molecular biology but still lacks the overall precision of traditional low-scale techniques. We developed a novel strategy of data processing linking search stringency to quality indicators for efficient detection of low-level, regulated genes.
Raffelsberger, Wolfgang   +4 more
openaire   +3 more sources

Assessing Malaysia’s Business Cycle indicators [PDF]

open access: yes
An empirical assessment shows that Malaysia’s business cycle indicators can be improved. Turning point detection is not impressive, especially for troughs. Lead times are also variable.
Michael Meow-Chung Yap
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Higher Education Outcomes, Graduate Employment and University Performance Indicators [PDF]

open access: yes
Official employment-related Performance Indicators in UK Higher Education are based on the population of students responding to the First Destination Supplement (FDS).
Bratti, Massimiliano   +3 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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