Results 51 to 60 of about 702,208 (349)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Simulation-Based Reliability Design Optimization Method for Industrial Robot Structural Design

open access: yesApplied Sciences, 2023
Robots are main elements in Industry 4.0. Research on the design optimization of robots has a great significance in manufacturing industries. There inevitably exist various uncertainties in robot design that have an important influence on the reliability
Li-Xiang Zhang   +3 more
doaj   +1 more source

The evaluation of light conditions influence and corrections upon Doppler blood perfusion imagining [PDF]

open access: yes, 2016
The paper deals with theoretical and experimental research of the ambient light influence upon the measuring reliability of the perfusion maps by the laser Doppler method using the device PeriScan PIM 3.
Bryjová, Iveta   +4 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Robust Dynamic Selection of Tested Modules in Software Testing for Maximizing Delivered Reliability [PDF]

open access: yes, 2017
Software testing is aimed to improve the delivered reliability of the users. Delivered reliability is the reliability of using the software after it is delivered to the users. Usually the software consists of many modules. Thus, the delivered reliability
Cai, Kai-Yuan   +3 more
core  

Reliability-based design optimization using kriging surrogates and subset simulation

open access: yes, 2011
The aim of the present paper is to develop a strategy for solving reliability-based design optimization (RBDO) problems that remains applicable when the performance models are expensive to evaluate.
Bourinet, J. -M.   +2 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Construction of an Integrated Framework for Complex Product Design Manufacturing and Service Based on Reliability Data

open access: yesMachines, 2022
With the application of new-generation information technology in the full life cycle process of a complex product, it is showing the characteristics of multi-source, real-time, heterogeneous, cross-domain transmission.
Jinfeng Wang   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Distilling Information Reliability and Source Trustworthiness from Digital Traces

open access: yes, 2017
Online knowledge repositories typically rely on their users or dedicated editors to evaluate the reliability of their content. These evaluations can be viewed as noisy measurements of both information reliability and information source trustworthiness ...
Aalen O.   +15 more
core   +1 more source

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