Results 81 to 90 of about 512,561 (264)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Reliability sensitivity analysis using axis orthogonal importance Latin hypercube sampling method

Advances in Mechanical Engineering, 2019
In this article, a combined use of Latin hypercube sampling and axis orthogonal importance sampling, as an efficient and applicable tool for reliability analysis with limited number of samples, is explored for sensitivity estimation of the failure ...
Wei Zhao, YangYang Chen, Jike Liu
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Simultaneous analysis of structural reliability and parameter sensitivity of flexible pavements

Case Studies in Construction Materials
To account for the influence of uncertainties in pavement design, adopting a probabilistic limit state-based approach for asphalt pavement structural design is currently the prevailing solution. However, due to the numerous parameters involved in asphalt
Xiaosi Yang, Hongzhou Zhu, Song Yang, Qiqi Tan, Li Ou   +4 more
doaj   +1 more source

Reliability, sensitivity, and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors. [PDF]

Hum Brain Mapp, 2021
Kolskår KK, Richard G, Alnaes D, Dørum ES, Sanders AM, Ulrichsen KM, Sánchez JM, Ihle-Hansen H, Nordvik JE, Westlye LT.   +9 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Reliability and sensitivity analysis of honeycomb sandwich composite radome structure

Xibei Gongye Daxue Xuebao
Radome is an important structural component for protecting an aircraft′s radar antenna and is usually located in the nose part of the aircraft. A method for evaluating the reliability and sensitivity of a honeycomb sandwich composite radome structure ...
SONG Haizheng, ZHOU Chunping, WEI Zheng, LI Lei, ZHOU Changcong   +4 more
doaj   +1 more source

Reliability sensitivity numerical analysis of mechanical structure based on gamma processes

Advances in Mechanical Engineering, 2016
Using random variables to describe uncertain parameters in structural systems, its initial strength and the evolution process of the strength degradation is regarded as the Gamma process.
Yanshan Zhang, Zhengmao Yang
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A reliability-based robust design for structural components with a variable cross section under limited probabilistic information

Advances in Mechanical Engineering, 2017
In engineering design, structural components with variable cross sections are extensively employed due to their excellent mechanical properties. From a strength and stiffness perspective, structural components with a uniform cross section are not always ...
Tianxiao Zhang, David He
doaj   +1 more source