Results 41 to 50 of about 505,866 (269)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A retail audit of mosquito control products in Bidibidi refugee settlement, northwestern Uganda
Malaria JournalBackground Uganda remains one of the highest malaria burden countries globally, with refugee populations disproportionately affected. While government-led initiatives, such as free distribution of insecticide-treatesd nets (ITNs) and indoor residual ...
Kaci D. McCoy +9 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The role of religion in the formation of cross-community relationships
Forced Migration Review, 2014 Spiritual life is a priority in many conflict-affected communities, perhaps especially in situations of displacement. It is rarely prioritised by aid agencies, yet may be central to the formation and maintaining of strong and effective cross-community ...
Sadia Kidwai +2 more
doaj
Frontiers in Public Health, 2016 The U.S. Agency for International Development Feed the Future Mawa Project—led by Catholic Relief Services—aims to improve food and economic security for farming households in Zambia’s Eastern Province.
Ingrid M Weiss +5 more
doaj +1 more source
BMC Health Services Research, 2020 Background The indications for general anesthesia (GA) in obstetric settings, which are determined in consideration of maternal and fetal outcome, could be affected by local patterns of clinical practice grounded in unique situations and circumstances ...
Takamitsu Ikeda +11 more
doaj +1 more source
Creating a Tool to Measure Children's Wellbeing: A PSS Intervention in South Sudan
Journal on Education in Emergencies, 2021 Since 2015, more than 560,000 South Sudanese primary school children have received psychosocial support (PSS) through the USAID-funded Integrated Essential Emergency Education Services program implemented by UNICEF.
Moses Olayemi +6 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
JA Clinical ReportsBackground Spinal extradural arachnoid cysts (SEACs) can cause persistent pain after surgery. Combining spinal cord stimulation (SCS) with structured exercise therapy may aid long-term pain modulation.
Akari Ikemura +8 more
doaj +1 more source