Results 41 to 50 of about 209,742 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The role of morphometric indicators of relief in the assessment of ecogeomorphological conditions in the Fuzuli administrative region

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Геологія. Географія. Екологія
In the assessment of ecogeomorphological conditions, morphometric indicators of relief (such as slope, elevation differences, horizontal and vertical fragmentation, exposure etc.) make it possible to determine the intensity of natural processes and the ...
Samira Abushova
doaj   +1 more source

Assessment of the Vulnerability of the Coast of Lake Alakol to Modern Geomorphological Processes of Relief Formation

Land, 2023
Over the last few decades, increasing water levels of Lake Alakol have led to the activation of processes of modern relief formation of the coastal territory. This study will make it possible to assess the vulnerability of the lake shore to modern relief-
Akhmetkal Medeu, Adilet Valeyev, Farida Akiyanova, Yuisya Lyy, Gulnura Issanova, Yongxiao Ge   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Geomagnetic Basement Relief of the Northern Taiwan Area

Terrestrial, Atmospheric and Oceanic Sciences, 2001
A detailed magnetic survey has been carried out in the northern Taiwan area in order to determine the topographic surface of the magnetic basement. This survey covers an area of about 900 km2, and totally the observation point is 269. After geomagnetic corrections of the observed data, the magnetic anomaly map was obtained. For the purpose of resolving
Kuang-Jung Chen, Chao-Ming Wang, Shu-Kun Hsu, Wen-Tzong Liang   +3 more
openaire   +2 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Hot-spot congestion relief in public-area wireless networks [PDF]

Proceedings Fourth IEEE Workshop on Mobile Computing Systems and Applications, 2003
Wireless LAN administrators are often called upon to deal with the problem of sporadic user congestion at certain popular spaces ("hot-spots") within the network. To address this problem, we describe and evaluate two new approaches, explicit channel switching and network-directed roaming for providing hot-spot congestion relief while maintaining pre ...
Anand Balachandran, Paramvir Bahl, Geoffrey M. Voelker   +2 more
openaire   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Exploring the Impact of Campus Landscape Visual Elements Combination on Short-Term Stress Relief among College Students: A Case from China

Buildings
Although the effect of campus landscape space on stress relief among college students has been confirmed, few existing studies have considered the impact on stress recovery from the perspective of factor combination, and the key visual elements and the ...
Hui He, Tong Zhang, Qinghao Zhang, Sheng Rong, Yihe Jia, Fengqian Dong   +5 more
doaj   +1 more source