Results 61 to 70 of about 88,194 (298)
Gender perspective in leprosy programs: A critical literature review [PDF]
Objective: To analyze the gender perspective in articles on community participation programs carried out with people affected by leprosy. Methodology: A critical literature review was carried out with an ad-hoc guide based on three documents related to ...
Gil-González, Diana +2 more
core +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Rural Emergency Relief in Washington with Attention to Characteristics of Rural Relief Households
Topics include the rural emergency relief perspective, characteristics of rural relief households in five rural counties June through December 1935, and rural relief among farm laborers in the Yakima ...
Pritchard, Mae +2 more
core +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
What a relief! The pleasure of threat avoidance
Relief, a pleasurable experience, is often triggered by successful threat avoidance. Although relief is regarded as the positive reinforcer for avoidance behavior, its rewarding nature remains to be demonstrated.
Bram Vervliet, Tom Beckers, Lu Leng
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Byzantium’s arms and armours were researched by many historians. For that reason, the military history of the medieval Roman Empire enjoyed a dominant position in medieval historiography, with the consequence that very often the military history of small
Dmytro Dymydyuk
doaj +1 more source
The Dynamics of Relief Spending and the Private Urban Labor Market During the New Deal [PDF]
During the New Deal the Roosevelt Administration dramatically expanded relief spending to combat extraordinarily high rates of unemployment. We examine the dynamic relationships between relief spending and local private labor markets using a new panel ...
Todd C. Neumann +2 more
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