Results 31 to 40 of about 303,120 (311)

Humanitarian health education and training state-of-the-art: a scoping review

Frontiers in Public Health
IntroductionIn the past decade, humanitarian emergencies have been increasing, leading to an higher demand for humanitarian health professionalization.
Awsan Bahattab, Awsan Bahattab, Monica Trentin, Monica Trentin, Ives Hubloue, Francesco Della Corte, Francesco Della Corte, Luca Ragazzoni, Luca Ragazzoni   +8 more
doaj   +1 more source

Comparison of Relief Shading Techniques Applied to Landforms

ISPRS International Journal of Geo-Information, 2020
As relief influences disposition of all the other objects displayed on maps, terrain representation plays one of the key roles in the map creation process.
Marianna Farmakis-Serebryakova, Lorenz Hurni   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health needs assessment: development of a simplified risk probability scale design for rapid mental health screening in emergency frontline rescue teams

Frontiers in Public Health
BackgroundEmergency frontline rescue workers during the COVID-19 pandemic faced elevated psychological risks, yet existing tools lack specificity for crisis contexts.AimTo develop a simplified risk probability scale (SRPS) tailored for rapid self ...
Yifei Chen, Yan Bo, Zhuanzhuan Han, Guowei Fan   +3 more
doaj   +1 more source

Reconnoitering NGOs strategies to strengthen disaster risk communication (DRC) in Pakistan: A conventional content analysis approach

Heliyon, 2023
Risk communication is crucial since individuals need to understand how they are at risk and what proper steps to deal with flood events. Sharing information with the public opens the door for two-way communication about risks, wherein you learn about ...
Ashfaq Ahmad Shah, Ayat Ullah, George T. Mudimu, Nasir Abbas Khan, Abid Khan, Chong Xu   +5 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Handikappade och 1800-talets fattigvård

Kulturella Perspektiv, 2007
This article is based on local poor relief records from parishes in the Sundsvall Region, Sweden. The period described, i.e. decades around the mid-19th century, is characterized by rapid shifts from a rural society and to an industrialized one.
Ulf Drugge
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source