Results 51 to 60 of about 1,577,016 (348)

Nurses Alumni Association Bulletin, Fall 1997 [PDF]

, 1997
1997-1998 Meeting Dates Calendar 1998 Annual Luncheon-Meeting Notice Officers and Committee Chairs Bulletin Publication Committee 1997-1998 Meeting Dates Calendar The President\u27s Message Treasurer\u27s Report Trivia and News About Our Graduates ...
Henrie-Strup, Sue, McVail, Maureen, Piersol, Betty, Prisnock, Elizabeth K., Smith, Marian E., Summers, Margaret   +5 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Nurses Alumni Association Bulletin, Fall 1999 [PDF]

, 1999
1999-2000 Meeting Dates Calendar 2000 Annual Luncheon-Meeting Notice Fall Social Officers and Committee Chairs Bulletin Publication Committee The President\u27s Message Treasurer\u27s Report News About Our Graduates History of The Nurses Relief Fund ...
Piersol, Betty, Prisnock, Elizabeth K., Smith, Marian E., Summers, Margaret   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Remedies Symposium, Remedial Discretion in Constitutional Adjudication: A Codicil [PDF]

, 2018
This symposium paper elaborates on two questions raised by the author’s prior work, Remedial Discretion in Constitutional Adjudication. That paper disagreed with calls for a revival of non-retroactive judicial rulings to facilitate more constitutional ...
Greabe, John M
core   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

One Year Follow-up of a Randomized, Double-Blind, Placebo-Controlled Trial of Percutaneous Peripheral Nerve Stimulation for Chronic Neuropathic Pain Following Amputation [PDF]

, 2019
INTRODUCTION Over 85% of patients experience residual limb (RLP) and/or phantom limb (PLP) pain following amputation. Peripheral nerve stimulation (PNS) is a non-opioid approach to relieve postamputation neuropathic pain.
Boggs, Josh W, Cohen, Steven P, Crosby, Nate, Desai, Mehul J, Gilmore, Christopher, Hunter, Corey, Ilfeld, Brian M, Kapural, Leonardo, Li, Sean, Mak, John, Nader, Antoun, Rauck, Richard, Rosenow, Joshua M   +12 more
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Nurses Alumni Association Bulletin, Fall 1996 [PDF]

, 1996
1996-1997 Meeting Dates Calendar 1997 Annual Luncheon-Meeting Notice Inside Officers and Committee Chairs Bulletin Publication Committee 1996-1997 Meeting Dates Calendar The President\u27s Message Treasurer\u27s Report News About Our Graduates Letter To ...
Fireman, Deborah, Herndon, Nicole, Piersol, Betty, Prisnock, Elizabeth K., Smith, Marian E., Summers, Margaret   +5 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source