Results 81 to 90 of about 1,577,016 (348)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Izdelava reliefne karte dela Pomurja : Production of the relief map of a part of Pomurje [PDF]

open access: yesGeodetski Vestnik, 2006
Relief maps are three-dimensional representations of the Earth’s surface. In contrast to traditional 2D maps, where the relief is represented indirectly, the relief maps are intended for direct representation of the relief.
Slavko Zec, Dušan Petrovič
doaj  

Crisis on the game board – a novel approach to teach medical students about disaster medicine

open access: yesGMS Journal for Medical Education, 2018
Introduction: Every year, natural and other disasters cause significant loss of life around the world. This calls for an improved response from, among others, the health professions to strengthen disaster medicine, whether relating to prevention ...
Drees, Simon   +2 more
doaj   +1 more source

Occupational structures, migration, religion and poor relief in nineteenth century urban Ireland [PDF]

open access: yes
Patterns of poor relief varied greatly amongst nineteenth century Irish cities. To date, however, there has been little examination of the reasons behind these divergences.
Cousins, Mel
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Leadership of Humanitarian Organizations Working in Less Developed Countries: A Best Practices Analysis [PDF]

open access: yes, 2016
Many people from the developed world, who intend to help the poor in less developed countries, actually end up doing harm by creating more dependence, demonstrating ignorance of the local culture, not understanding the importance of long-term ...
Oliphant, John
core   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Reduction of Noise and Vibration of Spur Gear by Using Asymmetric Teeth Profiles with Tip Relief

open access: yesJournal of Engineering, 2015
Reduction of noise and vibration in spur gear experimentally by using asymmetric teeth profiles with tip relief was presented. Both of classical (symmetric) and asymmetric (with and without tip relief) spur gears are used in this work.
Mohammad Qasim Abdullah, Prof. Dr.   +2 more
doaj   +2 more sources

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