Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core +1 more source
Graphene edge structures: Folding, scrolling, tubing, rippling and twisting
Conventional three-dimensional crystal lattices are terminated by surfaces, which can demonstrate complex rebonding and rehybridisation, localised strain and dislocation formation. Two dimensional crystal lattices, of which graphene is the archetype, are
Ewels, Christopher P. +5 more
core +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Caracterización morfoestructural del sector Mucaral, sureste de Mayarí
Se caracterizó el relieve del sector Mucaral y las estructuras que lo condicionan, a partir de las mediciones de campo y análisis morfométrico de las formaciones. Se utilizaron los métodos morfométricos para determinar los rasgos distintivos del relieve
Adrian Urrutia-Meriño
doaj
Relieving the fermionic and the dynamical sign problem: Multilevel Blocking Monte Carlo simulations [PDF]
This article gives an introduction to the multilevel blocking (MLB) approach to both the fermion and the dynamical sign problem in path-integral Monte Carlo simulations. MLB is able to substantially relieve the sign problem in many situations. Besides an
Egger, R., Mak, C. H.
core +1 more source
Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira +10 more
wiley +1 more source
El relieve, factor para la génesis, desarrollo y gestión del riesgo
Se expone la importancia que tiene el relieve como variable de origen, desarrollo y gestión del riesgo. Asimismo, se presenta la síntesis de algunos desastres ocurridos en el mundo y en México y se señala la vinculación que poseen con el relieve.
Luis Miguel Espinosa Rodríguez +2 more
doaj
Does corruption relieve foreign investors of the burden of taxes and capital controls? [PDF]
In a sample of fourteen source countries making bilateral investments in forty five countries, the author finds that taxes, capital controls, and corruption, all have large, statistically significant negative effects on foreign investment.
Shang-Jin Wei
core

