Results 101 to 110 of about 126,238 (250)
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
The effects of geomorphic controls on sediment yield in the Andean Rivers of Colombia
This paper examines sediment yield rates and its response to control variables in the principal rivers of Colombian draining into the Caribbean and Pacific coasts. Based on a multi-year dataset of sediment load from six rivers, including Mira, Patía, and
Juan D. Restrepo +2 more
doaj
Cartografía del relieve en el altiplano de Santa Rosa de Osos [PDF]
Resumen: eI relieve de la Cordillera Central en Antioquia consiste en un sistema escalonado de altiplanos rodeado por un relieve montañoso tropical de cañones ramificados. Ambas unidades de relieve están enmarcadas lateralmente por el sistema de Falla de
Cabrera, Kenneth Roy +3 more
core
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source
Capilla del Sagrado Corazón. Presbiterio. Relieve.-Anónimo Granadino.- El retablo presenta como elementos decorativos placas recortadas, estípites, rocallas, motivos vegetales y ...
Gómez Alvarez de Salina, Inmaculada
core +9 more sources
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang +13 more
wiley +1 more source

