Results 31 to 40 of about 385,829 (304)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Mapa de las unidades de relieve de España
, 2011 La imagen muestra las unidades del relieve de España y de las islas Baleares, siendo: el planalto, las cordilleras interiores, exteriores y que cercan el planalto, las depresiones perifericas, las planicies del litoral y las islas de origen ...
Bermúdez, José Alberto
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Investigaciones Geográficas, 2009 De acuerdo con un enfoque geomorfológico tipológico y la aplicación de los métodos del análisis morfoestructural, fueron determinados los principales tipos morfoestructurales del relieve del estado de Oaxaca, el territorio mexicano más complejo, desde el
José Ramón Hernández Santana +2 more
doaj +3 more sources
Mapa de las unidades de relieve de España
, 2016 Ensino Fundamental Final::GeografiaLa imagen muestra las unidades del relieve de España y de las islas Baleares, siendo: el planalto, las cordilleras interiores, exteriores y que cercan el planalto, las depresiones perifericas, las planicies del litoral ...
Bermúdez, José Alberto
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Revista Cubana de Meteorología, 2013 El Sol es la principal fuente de energía para la mayoría de los procesos y fenómenos que ocurren en el planeta Tierra. Los cambios sistemáticos que experimenta la energía solar recibida en diversos lugares y en distintas épocas influyen, decisivamente ...
Yosdany González Jaime +2 more
doaj
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source