Results 41 to 50 of about 126,238 (250)
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
El Sol es la principal fuente de energía para la mayoría de los procesos y fenómenos que ocurren en el planeta Tierra. Los cambios sistemáticos que experimenta la energía solar recibida en diversos lugares y en distintas épocas influyen, decisivamente ...
Yosdany González Jaime +2 more
doaj
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Mapa geomorfológico del municipio de Banes a escala 1:100000
Se confeccionó el mapa geomorfológico del área centro septentrional de la provincia de Holguín, prestándole especial interés a la zona de Banes. Para esto fueron utilizados métodos morfométricos que, en conjunto con los mapas temáticos de la zona y los ...
Dihosvanys L. Arias-González
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Cuarta unidad del módulo “Tallado de muebles”en la que se describe cómo hacer tallas en alto relieve así cómo el manejo correcto de gubias, buriles, sesgos y formones para realizar el tallado con las figuras bien detallada, precisión en los cortes y ...
Maestre, Guillermo +2 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

