Results 41 to 50 of about 1,091,662 (280)
Does turmeric relieve inflammatory conditions? [PDF]
Limited evidence suggests that turmeric and its active compound, curcumin, are effective for rheumatoid arthritis and other inflammatory conditions (strength of recommendation [SOR]: C, primarily low-quality cohort studies with small patient numbers ...
Judkins, Dolores Zegar, White, Brett
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Do nasal decongestants relieve symptoms? [PDF]
Oral and topical nasal decongestants result in a statistically significant improvement in subjective symptoms of nasal congestion and objective nasal airway resistance in adults' common colds (strength of recommendation [SOR]: A, based on randomized ...
Allen, Ginger +2 more
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Excess pressure by sutures in wound closure can lead to "cutting out" of sutures or to ischemia of tissue adjacent to the sutures. Excess pressure can be avoided by use of specific suture patterns or surgical procedures. The surgeon should select the simplest procedure and should consider, in order of preference, the use of subdermal sutures, tension ...
openaire +2 more sources
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core
The striped cuprate La$_{2-x}$Ba$_x$CuO$_4$ ($x=\frac18)$ undergoes several transitions below the charge-ordering temperature $T_{co}$ = 54 K. From Nernst experiments, we find that, below $T_{co}$, there exists a large, anomalous Nernst signal $e_{N,even}
Alidoust, N. +4 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
De acuerdo con un enfoque geomorfológico tipológico y la aplicación de los métodos del análisis morfoestructural, fueron determinados los principales tipos morfoestructurales del relieve del estado de Oaxaca, el territorio mexicano más complejo, desde el
José Ramón Hernández Santana +2 more
doaj +3 more sources
Role of connectivity in congestion and decongestion in networks
We study network traffic dynamics in a two dimensional communication network with regular nodes and hubs. If the network experiences heavy message traffic, congestion occurs due to finite capacity of the nodes.
Gupte, Neelima, Singh, Brajendra K.
core +2 more sources

