Results 71 to 80 of about 1,100,185 (299)
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
, 2007 The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Agroecosistemas, 2020 La calidad del suelo es una herramienta de valoración que facilita la aplicación de prácticas de manejo que promuevan sistemas agronómicos sostenibles. El objetivo de caracterizar varios usos de suelo en función de varias propiedades físicos-químicas del
Barrera León, Jenner +2 more
doaj
Scientific journals on Education in Spain: evolution and prospects for the future.
RELIEVE: Revista Electrónica de Investigación y Evaluación Educativa, 2014 The Spanish scientific journals on education have experience an exponential growth in recent decades. The reasons are closely related to the supranational policies of university quality assessment, with specific emphasis on research output with "impact".
Ruiz-Corbella, Marta +2 more
doaj +1 more source
Prosthetic urinary sphincter [PDF]
, 1981 A pump/valve unit for controlling the inflation and deflation of a urethral collar in a prosthetic urinary sphincter device is described. A compressible bulb pump defining a reservoir was integrated with a valve unit for implantation.
Helms, C. R., Smyly, H. M.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Mapa geomorfológico preliminar del municipio de Mayarí a escala 1: 100 000
Ciencia & Futuro, 2016 Se determinaron los tipos de relieve que conforman el municipio de Mayarí. Para esto se digitalizaron las hojas topográficas que conforman el área de estudio, obteniendo el modelo digital de la misma.
Sergio Greenidge-Moro
doaj
Psychometric analysis of a perception scale on the usefulness of Moodle in the University.
RELIEVE: Revista Electrónica de Investigación y Evaluación Educativa, 2014 Because of the acquired relevance of learning management systems in higher education, and the spread of the use of the Moodle platform in many academic institutions, a scale of perceived usefulness of the Moodle in this context is designed, and the ...
Olmos-Migueláñez, S. +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Ecosistemas y Recursos Agropecuarios, 2016 La cartografía de suelos contribuye a la plani cación de los sistemas agropecuarios, pero el nivel de reconocimiento con que se cuenta en México está desactualizado.
Joel Zavala-Cruz +4 more
doaj