Results 41 to 50 of about 141,840 (266)

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

open access: yesAdvanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang   +6 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

open access: yesAdvanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho   +6 more
wiley   +1 more source

The Strategic Role of Female Leadership in Arabic Language Education

open access: yesJurnal Al Bayan: Jurnal Jurusan Pendidikan Bahasa Arab
A phenomenological approach was used to examine the role of female academic leadership in managing and developing Arabic Language Education programs at higher education institutions or universities in Lampung, Indonesia.
Dwi Noviatul Zahra   +2 more
doaj   +1 more source

A Large Scale Multi‐Modal Workflow for Battery Characterization: From Concept to Implementation

open access: yesAdvanced Energy Materials, EarlyView.
Isolated characterization techniques produce independent datasets and single‐property insights. However, progressively more holistic interpretations of battery‐material behavior is needed in the future. Here we demonstrate a coordinated multimodal workflow enabling the correlation of heterogeneous datasets and the construction of multidimensional ...
François Cadiou   +34 more
wiley   +1 more source

Maqāṣid al-‘Ilm and Maqāṣid al-Bī’ah: A Dialogue between the Philosophy of Science and Ecotheology in the Environmental Crisis

open access: yesJurnal Inovasi Pendidikan dan Sains
The contemporary environmental crisis—marked by ecological degradation, climate change, and a weakening of ethical responsibility toward nature—demands a renewed integration between scientific knowledge and spiritual consciousness.
Husnul Haetami   +2 more
doaj   +1 more source

MXene‐Derived Highly Oriented TiN Enables Ta3N5 Photoanodes for Transmission‐Mode Bias‐Free Solar Water Splitting

open access: yesAdvanced Energy Materials, EarlyView.
This work reports 2D MXene‐derived TiN thin films with (111)‐preferred orientation for transparent Ta3N5 photoanodes, demonstrating effective electron transfer behavior. All‐nitride electron‐collection architecture based on MXene‐derived TiN and n‐GaN resolves a long‐standing materials bottleneck between photocarrier transport and light transmission in
Jin Wook Yang   +10 more
wiley   +1 more source

Eco-Theology–Based Deep Learning as a Paradigm for Environmentally Conscious Islamic Religious Education Learning

open access: yesJurnal Inovasi Pendidikan dan Sains
The The escalating global environmental crisis—reflected in climate change, ecological degradation, and declining environmental awareness—poses serious challenges for educational institutions, including Islamic Religious Education.
Jumaah Jumaah   +2 more
doaj   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

Soft Skills Development in Indonesian Islamic Higher Education: Institutional Practices and the SSDIHE Model for Society 5.0

open access: yesJournal of Education and Teaching
This study examines how leaders and lecturers at Islamic Higher Education Institutions in Indonesia conceptualize, implement, and evaluate soft skills development for students, with particular attention to its relevance in the Society 5.0 era.
Zulkifli Musthan   +3 more
doaj   +1 more source

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