Results 131 to 140 of about 5,858 (225)
Macrophages Contribute to Pulmonary Hypertension Associated With Sickle Cell Disease
This study investigated proteomic and metabolomic differences in pulmonary macrophages and the lung microenvironment to determine molecular pathways involved in Sickle Cell Disease associated pulmonary hypertension. We concluded that macrophages play a critical role in disease pathology by decrease pulmonary arterial muscularization. ABSTRACT Pulmonary
Christina Lisk +17 more
wiley +1 more source
Redewiedergabe reloaded? [PDF]
openaire +3 more sources
ABSTRACT Overcoming the strength–ductility trade‐off in face‐centered cubic (FCC) multi‐principal element alloys (MPEAs), particularly at cryogenic temperatures, remains a significant challenge. Here, a laser powder bed fusion (LPBF)–enabled direct aging strategy is employed to modify the precipitation behavior in a Ni53Fe20Cr23Nb4 (at%) alloy.
Xiaohui Qin +8 more
wiley +1 more source
Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa +18 more
wiley +1 more source
Sensory nerves regulate bone homeostasis in response to mechanical unloading or reloading: evidence from a spaceflight experiment and ground-based mechanical unloading models. [PDF]
Tsujino S +13 more
europepmc +1 more source
QuickProcess2 (QP2) unifies real‐time image visualization, automated multi‐pipeline data processing and experiment management into a single open‐source platform for synchrotron macromolecular crystallography beamlines, enabling live quality assessment and concurrent data reduction for both standard rotation and serial crystallography experiments.The ...
Qingping Xu +9 more
wiley +1 more source
A Unified Damage-Plasticity Constitutive Framework for Freeze-Thaw-Damaged Concrete Under Monotonic and Cyclic Compression. [PDF]
Gao P +5 more
europepmc +1 more source
SummaryThe base excess value (BE, mmol/L), not standard base excess (SBE), correctly calculated including pH, pCO2 (mmHg), sO2 (%) and cHb (g/dl) is a diagnostic tool for several in vivo events, e.g., mortality after multiple trauma or shock, acidosis, bleeding, clotting, artificial ventilation. In everyday clinical practice a few microlitres of blood (
openaire +3 more sources
geohabnet: An R package for mapping habitat connectivity for biosecurity and conservation
Abstract Habitat connectivity is critical for the conservation of endangered and endemic species, and conversely, it can hinder efforts to contain the spread of harmful biological agents. Here, we introduce geohabnet: a general, spatially explicit, network‐based R package for evaluating, estimating and mapping landscape connectivity from continuous ...
Aaron I. Plex Sulá +6 more
wiley +1 more source
Real world experience with faricimab in switched neovascular AMD and evaluation of reloading versus interval matching regimes. [PDF]
Brown FE, Mitra M.
europepmc +1 more source

