Results 51 to 60 of about 85,718 (254)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 1943 Map of entire site of Manzanar War Relocation Project, incl. airport, camp, reservoir, well, highways, and sewage plantMA-X-792-
Drawn: S.N. Traced: S.N.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Description of the Oregon Department of Transportation Relocation Assistance Program [PDF]
, 2011 "734-3772."Covers OCLC #1121478719 and OCLC #908859156.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core +1 more source
Ideologiska strategier och maskulin rationalitet
Kulturella Perspektiv, 2008 Kiruna is a relatively young and small town in the north of Sweden. Due to the expansion of the mining industry parts of the central Kiruna has to move a few kilometers in a northwest direction.
Bo Nilsson
doaj +1 more source
Pamphlet, The War Relocation Work Corps
, 1942 The War Relocation Work Corps Pamphlet, A Circular of Information for enlistees and their Families detailing the War Relocation Work Corps, its purpose and operation. Contains opening letter from M.S.
War Relocation Authority
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Commuting tools and residential location of suburbanization: evidence from Beijing
Urban, Planning and Transport Research, 2014 Since the 1990s, the population of Beijing has decentralized. This paper studies the relationship between residents’ commuting tools and their residential location during suburbanization by applying field survey data, statistical methods, and Geographic ...
Yongling Yao, Shuai Wang
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source