Results 61 to 70 of about 104,448 (312)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Transforming Novosibirsk into the capital of Siberia in the early 1920s [PDF]
Омский научный вестник: Серия "Общество. История. Современность"The development of Novonikolaevsk (Novosibirsk) and its transformation into a city of all-Siberian importance is connected with the construction of the Trans-Siberian Railway and the growth of the city’s economy due to its favorable geographical ...
S. A. Papkov
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Focused ultrasound guided relocation of kidney stones
Indian Journal of Urology, 2015 Purpose: Complete removal of all fragments is the goal of any intervention for urinary stones. This is more important in lower pole stones where gravity and spatial orientation of lower pole infundibulum may hinder spontaneous passage of fragments ...
Nitin Abrol, Nitin S Kekre
doaj +1 more source
Relocation of government activities as a regional policy measure [PDF]
In recent years there has been a growing interest towards relocation of government activities - moving civil service jobs away from capital to provincial regions, so from center to more peripheral regions - in Finland.
Johanna Yliskylä-Peuralahti
core
Interventions, 2006 Refugees’ experiences of living in non-Western urban settings are infrequently addressed outside those particular cities. This essay presents snapshots of refugees’ experiences of asylum in one such city, Cairo, where it is UNHCR which undertakes the refugee status determination process.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Not drowning but fighting: Pacific Islands activists
Forced Migration Review, 2015 Focusing on climate-induced migration, rather than mitigation, can be at odds with grassroots demands and can make the future uninhabitability of some Pacific Islands appear as a foregone conclusion.
Hannah Fair
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
One good reason to speak of ‘climate refugees’
Forced Migration Review, 2015 The concept of ‘environmental refugees’, or ‘climate refugees’, has been progressively abandoned, as having no legal basis. I want to argue that there are good reasons to use the term.
François Gemenne
doaj