Results 101 to 110 of about 156,934 (328)

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Complementary roles of slow-wave sleep and rapid eye movement sleep in emotional memory consolidation [PDF]

, 2014
Although rapid eye movement sleep (REM) is regularly implicated in emotional memory consolidation, the role of slow-wave sleep (SWS) in this process is largely uncharacterized.
Ambrosini, Baran, Born, Born, Cairney, Diekelmann, Diekelmann, Diekelmann, Diekelmann, Fischer, Frankland, Gais, Gais, Giuditta, Hoddes, Hu, Introini-Collison, Jones, Lewis, Maldjian, Maquet, Marr, Marrosu, Marshall, Marshall, McClelland, Oldfield, P. A. Lewis, Payne, Payne, Payne, Peigneux, Plihal, Plihal, Power, R. Power, Rasch, S. A. Cairney, S. J. Durrant, Slotnick, Sterpenich, Sterpenich, Stickgold, Stickgold, Tucker, Tzourio-Mazoyer, van Dongen, Wagner, Wagner, Walker, Walker, Wilhelm   +51 more
core   +1 more source

A prospective randomized crossover trial investigating melatonin versus sleep deprivation for sleep induction in nap electroencephalography

Epilepsia Open, EarlyView.
Abstract Objective Electroencephalography (EEG) plays a fundamental role in the diagnosis and classification of epilepsy, and inducing sleep during EEG can improve patient cooperation and enhance the detection of epileptiform activity. Despite its importance, there is currently no standardized approach for sleep induction in pediatric EEG recordings ...
Valentina De Giorgis, Costanza Varesio, Massimiliano Celario, Carlo Alberto Quaranta, Francesca Ferraro, Ludovica Pasca, Guido Fedele, Grazia Papalia, Michela Palmisani, Cinzia Fattore, Paola Rota, Valentina Franco   +11 more
wiley   +1 more source

Hypnotic and Sleep Quality–Enhancing Properties of Kavain in Sleep-Disturbed Rats

Journal of Pharmacological Sciences, 2009
The present study was performed to investigate the effects of kavain on the sleep-wake cycle in comparison with that of rilmazafone and diphenhydramine using sleep-disturbed rats.
Ryuki Tsutsui, Kazuaki Shinomiya, Yasuhiro Takeda, Yoshihito Obara, Yoshihisa Kitamura, Chiaki Kamei   +5 more
doaj   +1 more source

Monitoring sleep depth: analysis of bispectral index (BIS) based on polysomnographic recordings and sleep deprivation [PDF]

, 2015
© 2015 Springer Science+Business Media Dordrecht The assessment and management of sleep are increasingly recommended in the clinical practice. Polysomnography (PSG) is considered the gold standard test to monitor sleep objectively, but some practical ...
Alonso López, Joan Francesc, Antonijoan Arbós, Rosa Maria, Baxarias, Pilar, Giménez Badia, Sandra, Mañanas Villanueva, Miguel Ángel, Pujol, Anna, Romero Lafuente, Sergio   +6 more
core   +2 more sources

Late‐onset unexplained epilepsy as a risk factor for cognitive impairment and dementia: Protocol for a multi‐center prospective longitudinal observational study (ELUCID)

Epilepsia Open, EarlyView.
Abstract Objective Late‐onset unexplained epilepsy (LoUE), defined as epilepsy onset after age 55 without an obvious cause, is an important risk factor for dementia. Studies have shown that 10%–25% of individuals with LoUE develop dementia within 3–4 years following their first seizure.
Alice D. Lam, Emily L. Johnson, Rani A. Sarkis, Leah J. Blank, Tyler E. Gaston, Mouhsin M. Shafi, Rodrigo Zepeda, Kyle R. Pellerin, Nathalie Jette, Douglas N. Greve, Lori B. Chibnik, Rebecca E. Amariglio, Gad A. Marshall, M. Brandon Westover   +13 more
wiley   +1 more source

Sawtooth waves during REM sleep after administration of haloperidol combined with total sleep deprivation in healthy young subjects [PDF]

, 2002
We sought to examine the possible participation of dopaminergic receptors in the phasic events that occur during rapid eye movement (REM) sleep, known as sawtooth waves (STW).
Peres, Clovis de Araujo, Pinto Junior, L.R., Remesar-Lopez, Alberto Jorge, Russo, Regina Helena, Tufik, Sergio   +4 more
core   +3 more sources

Clock gene dysregulation in epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos, Arjune Sen, Francesca Panin, Krithika Sundararaman   +3 more
wiley   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham, KayLene Y. H. Yamada, Emma M. Rhodes, Agata. M. Rudolf, Wendy R. Hood   +4 more
wiley   +1 more source