Results 81 to 90 of about 49,936 (298)

Dreaming and Insomnia: Link between Physiological REM Parameters and Mentation Characteristics

Brain Sciences, 2020
(1) Background: An unresolved phenomenon of insomnia disorder is a discrepancy between objectively measured sleep and subjective complaints. It has been shown that rapid eye movement (REM) sleep might be especially vulnerable to an altered perception ...
Fee Benz, Dieter Riemann, Bernd Feige
doaj   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

The relationship between sleep disturbance and depression

, 2006
This paper focuses on several aspects of the relationship between sleep and depression, with particular attention to objective factors and subjective perceptions.
Mayers, Andrew G., David S. Baldwin, Baldwin, David S., Andrew G. Mayers, Mayers, A.G., Baldwin, D.S.   +5 more
core   +1 more source

Inter‐rater reliability and clinical utility of the BASED score in infantile epileptic spasms syndrome

Epileptic Disorders, EarlyView.
Abstract Objective Hypsarrhythmia is the classical EEG pattern of children with infantile epileptic spasms syndrome (IESS). Multifocal spikes, slow waves of large amplitude, and chaoticity are its main characteristics, but these lack clear definitions, and the interrater reliability (IRR) is poor.
T. P. Cramer, B. Johnsen, V. S. Hansen, E. Qerama, T. S. Engedal   +4 more
wiley   +1 more source

Evolutionary Origin of Distinct NREM and REM Sleep

Frontiers in Psychology, 2020
Sleep is mandatory in most animals that have the nervous system and is universally observed in model organisms ranging from the nematodes, zebrafish, to mammals.
Risa Yamazaki, Hirofumi Toda, Paul-Antoine Libourel, Yu Hayashi, Yu Hayashi, Kaspar E. Vogt, Takeshi Sakurai, Takeshi Sakurai   +7 more
doaj   +1 more source

Blood pressure dipping during REM and non-REM sleep in patients with moderate to severe obstructive sleep apnea

Scientific Reports, 2021
A limited number of papers have addressed the association between non-dipping-blood pressure (BP) obstructive sleep apnea (OSA), and no study has assessed BP-dipping during rapid eye movement (REM) and non-REM sleep in OSA patients.
Ahmed S. BaHammam, Mana Alshahrani, Salih A. Aleissi, Awad H. Olaish, Mohammed H. Alhassoon, Afnan Shukr   +5 more
doaj   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

Epilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing, Lirong Han, Dongjun Guo, Thomas J. Foutz, Michael Wong   +4 more
wiley   +1 more source

Selective REM sleep deprivation in narcolepsy

, 2011
Narcolepsy is characterized by excessive daytime sleepiness and rapid eye movement (REM) sleep abnormalities, including cataplexy. The aim of this study was to assess REM sleep pressure and homeostasis in narcolepsy.
MANH HOANG VU, Vu, Manh Hoang, Mathis, Johannes, Bassetti, Claudio L, CLAUDIO L. BASSETTI, CHRISTOPH HURNI, JOHANNES MATHIS, CORINNE ROTH, Roth, Corinne, Hurni, Christoph   +9 more
core   +1 more source

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

Epilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

Isolated Rem Sleep Behavior Disorder: A Model to Assess the Overnight Habituation of Emotional Reactivity

Clocks & Sleep
(1) Background: Phasic events in rapid eye movement (REM) sleep are a core feature of isolated REM behavior disorder (iRBD), which is often associated with emotion dysregulation.
Caterina Leitner, Viviana Greco, Francesca Casoni, Penelope A. Lewis, Luigi Ferini-Strambi, Andrea Galbiati   +5 more
doaj   +1 more source