Results 181 to 190 of about 696,853 (368)

Using sleep to enhance exposure treatment for anxious children: A pilot study

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar   +4 more
wiley   +1 more source

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

open access: yesCell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

Prognostic value of interictal epileptiform discharges on routine EEG in adults with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine whether interictal epileptiform discharges (IEDs) on routine electroencephalography (EEG) predict seizure recurrence in adults with established epilepsy. Methods We conducted a retrospective survival analysis of consecutive adults with epilepsy undergoing routine EEG at a tertiary center between 2018 and 2019.
Émile Lemoine   +6 more
wiley   +1 more source

The Effect of Baclofen on Alterations in the Sleep Patterns Induced by Different Stressors in Rats

open access: yesJournal of Pharmacological Sciences, 2009
We have previously reported that sleep patterns are significantly affected by both physical and psychological stress induced by a communication box ; however, the mechanism by which stress alters sleep patterns was not established.
Ranji Cui   +3 more
doaj  

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