Results 41 to 50 of about 156,934 (328)

A study on sleep apnea in patients with abnormal sewda type of depression

Traditional Medicine and Modern Medicine, 2020
Objective: To preliminarily investigate the clinical features and PSG in abnormal sewda-type depressive insomnia. Methods: A total of 127 abnormal sewda-type depressive insomnia patients were evaluated with overnight PSG, and 32 normal participants were ...
Aman Gul, Nassirhadjy Memtily, Pirdun Mijit, Palidan Wushuer, Ainiwaer Talifu, Mihriban Imin, Hua Rui, Zuhoumaer Nuermaimaiti   +7 more
doaj   +1 more source

The relationship between psychosocial job stressors and insomnia: The mediating role of psychological capital

Nursing Open, EarlyView., 2023
Abstract Aim This study aimed to examine the association of job‐related stressors and insomnia; to determine the association of psychological capital and insomnia; and to explore whether psychological capital mediates the association between job‐related stressors and insomnia among Chinese nurses. Design A cross‐sectional questionnaire survey.
Juan Du, Shi‐Zhe He, Min‐Jie Li, Chao Wu, Wen‐Kai Zheng, Lin‐Yuan Zhang, Chun‐Ni Heng, Chun‐Ping Ni, Hong‐Juan Lang   +8 more
wiley   +1 more source

Melanin-concentrating hormone (MCH): a new sleep factor?

Frontiers in Neurology, 2011
Neurons that utilize the neuropeptide melanin-concentrating hormone (MCH) as a neuromodulator are mainly located in the lateral hypothalamus and the incerto-hypothalamic area, and have widespread projections throughout the brain.
Pablo eTorterolo, Patricia eLagos, Jaime M Monti   +2 more
doaj   +1 more source

Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. [PDF]

PLoS ONE, 2013
GABA is the major inhibitory neurotransmitter in the mammalian central nervous system that has been strongly implicated in the regulation of sleep. GABA transporter subtype 1 (GAT1) constructs high affinity reuptake sites for GABA and regulates GABAergic
Xin-Hong Xu, Wei-Min Qu, Min-Juan Bian, Fang Huang, Jian Fei, Yoshihiro Urade, Zhi-Li Huang   +6 more
doaj   +1 more source

Neurobehavioral Associations with NREM and REM Sleep Architecture in Children with Autism Spectrum Disorder

Children, 2022
Objective: Insomnia and daytime behavioral problems are common issues in pediatric autism spectrum disorder (ASD), yet specific underlying relationships with NonRapid Eye Movement sleep (NREM) and Rapid Eye Movement (REM) sleep architecture are ...
Jennifer Nguyen, Bo Zhang, Ellen Hanson, Dimitrios Mylonas, Kiran Maski   +4 more
doaj   +1 more source

Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep [PDF]

, 2014
Rapid eye movement (REM) sleep is an important component of the natural sleep/wake cycle, yet the mechanisms that regulate REM sleep remain incompletely understood.
Brown, Emery N., Gelwan, Noah A., Goldblum, Rebecca R., Kenny, Jonathan Dillion, Lin, Yingxi, Nolan, Michael A., Ramos, Daniel M., Van Dort, Christa, Wang, Karen, Weng, Feng-Ju, Wilson, Matthew A., Zachs, Daniel, Zheng, Shu   +12 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism

Frontiers in Neuroscience, 2014
In accordance with the prominent role of orexins in the maintenance of wakefulness via activation of orexin-1 (OX1R) and orexin-2 (OX2R) receptors, various dual OX1/2R antagonists have been shown to promote sleep in animals and humans.
Christine eDugovic, Jonathan E Shelton, Sujin eYun, Pascal eBonaventure, Brock T Shireman, Timothy W Lovenberg   +5 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Antidepressant suppression of REM and spindle sleep impairs hippocampus-dependent learning and memory but fosters striatal-dependent strategies [PDF]

, 2011
REM sleep enhances hippocampus-dependent associative memory but has little impact on striatal-dependent procedural learning. Antidepressant medications like desipramine (DMI) inhibit rapid-eye-movement (REM) sleep but it is little understood how ...
Alain Watts, Gina Poe, Howard Gritton, Jamie Sweigart   +3 more
core   +1 more source