Results 51 to 60 of about 472,554 (253)

A study on sleep apnea in patients with abnormal sewda type of depression

Traditional Medicine and Modern Medicine, 2020
Objective: To preliminarily investigate the clinical features and PSG in abnormal sewda-type depressive insomnia. Methods: A total of 127 abnormal sewda-type depressive insomnia patients were evaluated with overnight PSG, and 32 normal participants were ...
Aman Gul, Nassirhadjy Memtily, Pirdun Mijit, Palidan Wushuer, Ainiwaer Talifu, Mihriban Imin, Hua Rui, Zuhoumaer Nuermaimaiti   +7 more
doaj   +1 more source

Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism

Frontiers in Neuroscience, 2014
In accordance with the prominent role of orexins in the maintenance of wakefulness via activation of orexin-1 (OX1R) and orexin-2 (OX2R) receptors, various dual OX1/2R antagonists have been shown to promote sleep in animals and humans.
Christine eDugovic, Jonathan E Shelton, Sujin eYun, Pascal eBonaventure, Brock T Shireman, Timothy W Lovenberg   +5 more
doaj   +1 more source

Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. [PDF]

PLoS ONE, 2013
GABA is the major inhibitory neurotransmitter in the mammalian central nervous system that has been strongly implicated in the regulation of sleep. GABA transporter subtype 1 (GAT1) constructs high affinity reuptake sites for GABA and regulates GABAergic
Xin-Hong Xu, Wei-Min Qu, Min-Juan Bian, Fang Huang, Jian Fei, Yoshihiro Urade, Zhi-Li Huang   +6 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Neurobehavioral Associations with NREM and REM Sleep Architecture in Children with Autism Spectrum Disorder

Children, 2022
Objective: Insomnia and daytime behavioral problems are common issues in pediatric autism spectrum disorder (ASD), yet specific underlying relationships with NonRapid Eye Movement sleep (NREM) and Rapid Eye Movement (REM) sleep architecture are ...
Jennifer Nguyen, Bo Zhang, Ellen Hanson, Dimitrios Mylonas, Kiran Maski   +4 more
doaj   +1 more source

Antidepressant suppression of REM and spindle sleep impairs hippocampus-dependent learning and memory but fosters striatal-dependent strategies [PDF]

, 2011
REM sleep enhances hippocampus-dependent associative memory but has little impact on striatal-dependent procedural learning. Antidepressant medications like desipramine (DMI) inhibit rapid-eye-movement (REM) sleep but it is little understood how ...
Jamie Sweigart, Alain Watts, Howard Gritton, Gina Poe   +3 more
core  

The European starling (Sturnus vulgaris) shows signs of NREM sleep homeostasis but has very little REM sleep and no REM sleep homeostasis [PDF]

, 2020
Most of our knowledge about the regulation and function of sleep is based on studies in a restricted number of mammalian species, particularly nocturnal rodents. Hence, there is still much to learn from comparative studies in other species.
Vyssotski, Alexei L., Rattenborg, Niels C., Meerlo, Peter, van Hasselt, Sjoerd J.; id_orcid, Rusche, Maria, Meerlo, Peter; id_orcid, van Hasselt, Sjoerd J., Verhulst, Simon; id_orcid, Verhulst, Simon, Vyssotski, Alexei L, van Hasselt, Sjoerd J, Rattenborg, Niels C   +11 more
core   +2 more sources

Dopamine neurons in the ventral tegmental area modulate REM sleep. [PDF]

, 2023
International audienceidentified periods of 'active sleep' that are marked by rapid-eye-movements that alternate with 'quiescent sleep' periods in human infants.
Luppi, Pierre, Shiromani, Priyattam, Mahoney, Carrie E, Jimmy J Fraigne, John Peever, Antoine Adamantidis, Adamantidis, Antoine, Peever, John, Mahoney, Carrie, Fraigne, Jimmy J, Fraigne, Jimmy, Shiromani, Priyattam J, Priyattam J Shiromani, Adamantidis, Antoine Roger, Pierre H Luppi, Weber, Franz, De Luca, Roberto, Roberto De Luca, Carrie E Mahoney, Franz Weber, Luppi, Pierre H   +20 more
core   +2 more sources

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source