Results 131 to 140 of about 33,863 (342)
ABSTRACT Obstructive Sleep Apnoea (OSA) is a common heterogenous sleep disorder that is associated with a wide range of comorbidities and consequences, including the development of neurocognitive and cardiometabolic disorders. The heterogeneity of OSA necessitates a precision medicine approach to accurately diagnose this condition and to effectively ...
GM Stewart, BK Tong, PA Cistulli
wiley +1 more source
Sleep‐disordered breathing – clinical spectrum
ABSTRACT The clinical spectrum of sleep‐disordered breathing comprises a range of diverse conditions including obstructive sleep apnoea, central sleep apnoea and sleep‐related hypoventilation syndromes. These distinct conditions have specific diagnostic features and are managed differently from one another.
AM Mohammadieh, ASL Chan, PA Cistulli
wiley +1 more source
MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies [PDF]
Melissa E. Murray+20 more
openalex +1 more source
Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core +1 more source
Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder [PDF]
Real-time quaking-induced conversion (RT-QuIC) assay detects misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies Parkinson disease and dementia with Lewy bodies.
Arqueros, Aurora+14 more
core +1 more source
Robin Sequence: From Dilemmas to Developing an Adaptable Standardized Stepwise Approach
ABSTRACT Aim To review the literature to identify key issues causing variation in clinical practice, assess the knowledge gap, and develop a standardised pathway for managing upper airway obstruction (UAO) in infants with Robin sequence (RS). Methods The tripartite framework of evidence‐based practice, which included a systematic review of the ...
Dimple Goel+5 more
wiley +1 more source
Alexithymia Associated with Nightmare Distress in Idiopathic REM Sleep Behavior Disorder [PDF]
Isabelle Godin+3 more
openalex +1 more source
Using sleep to enhance exposure treatment for anxious children: A pilot study
Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar+4 more
wiley +1 more source
Objective To investigate the changes of transcranial sonography (TCS) in patients with rapid eye movement sleep behavior disorder (RBD). Methods Fifteen patients fulfilled the diagnostic criteria of RBD according to International Classification of ...
Xu-dong LI+9 more
doaj
Progress on the development of Class A GPCR‐biased ligands
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales+20 more
wiley +1 more source