Results 11 to 20 of about 33,863 (342)

Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder [PDF]

Nature Communications, 2018
Despite decades of research, there is a persistent debate regarding the localization of GABA/glycine neurons responsible for hyperpolarizing somatic motoneurons during paradoxical (or REM) sleep (PS), resulting in the loss of muscle tone during this ...
Arthaud Sébastien, Brischoux Frédéric, Clément Olivier, Fort Patrice, Lazarus Michael, Libourel Paul-Antoine, Luppi Pierre-Hervé, Valencia Garcia Sara   +7 more
core   +5 more sources

REM sleep behavior disorder (RBD)

Neurobiology of Disease, 2020
Since its first description in 1986 by Dr. Carlos Schenck, and his group's subsequent report of the delayed emergence of a Parkinsonian disorder in idiopathic RBD patients one decade later, RBD has emerged in recent years as one of the most promising markers of prodromal Parkinson's (References 2, 3). RBD is present in 25-58% of patients with Parkinson'
Michele T. Hu
doaj   +6 more sources

Melatonin therapy for REM sleep behavior disorder [PDF]

Psychiatry and Clinical Neurosciences, 2001
AbstractRapid eye movement sleep behavior disorder (RBD) is a parasomnia with clinical symptoms that include punching, kicking, yelling and leaping out of bed in sleep. Polysomnographic (PSG) finding showed REM sleep without muscle atonia. Clonazepam is generally used for treating RBD symptoms but melatonin was reported to be effective so we ...
Tatayu Kotorii, Katsuyasu Yamamoto, Yoshinori Etoh, Masaki Mukai, Hisao Maeda, Hiroharu Ohshima, Noboru Takeuchi, Yuji Hashizume, Masachika Ohshima, Naohisa Uchimura   +9 more
openaire   +4 more sources

Diagnostic tools for REM sleep behavior disorder [PDF]

Sleep Medicine Reviews, 2012
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by loss of muscle atonia during REM sleep that results in motor behaviors. Diagnosis of RBD involves a clinical interview in which history of dream enactment behaviors is elicited and a subsequent overnight polysomnography (PSG) evaluation to assess for REM sleep ...
Ariel B. Neikrug, Sonia Ancoli-Israel
openaire   +4 more sources

Neurophysiological basis of rapid eye movement sleep behavior disorder:Informing future drug development [PDF]

Nature and Science of Sleep, 2016
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by a history of recurrent nocturnal dream enactment behavior and loss of skeletal muscle atonia and increased phasic muscle activity during REM sleep: REM sleep without ...
Christensen, Julie Anja Engelhard, Jennum, Poul, Zoetmulder, Marielle   +2 more
core   +4 more sources

Brainstem and Spinal Cord Circuitry Regulating REM Sleep and Muscle Atonia [PDF]

PLoS ONE, 2011
Previous work has suggested, but not demonstrated directly, a critical role for both glutamatergic and GABAergic neurons of the pontine tegmentum in the regulation of rapid eye movement (REM) sleep.To determine the in vivo roles of these fast-acting ...
B Zernicki, BF Boeve, Bradford B. Lowell, C Anaclet, C Anaclet, C Scherfler, Christelle Anaclet, E Sapin, G Vanini, G Vanni-Mercier, H Braak, HL Wang, J Lu, J Lu, JF Gagnon, JM Siegel, JM Siegel, JP Sastre, Jun Lu, K Sakai, K Yoshida, Linh Vong, M Jouvet, Martina Krenzer, Nishang Wang, O Clement, P Fuller, Patrick M. Fuller, PM Fuller, Q Tong, Q Tong, R Boissard, R Boissard, R Vetrivelan, Ramalingam Vetrivelan, S Crochet, S Kaur, Shin Yamazaki, T Mochizuki, TC Chou, Z Xi   +40 more
core   +5 more sources

REM Sleep Behavior Disorder and Prodromal Neurodegeneration - Where are We Headed? [PDF]

Tremor and Other Hyperkinetic Movements, 2013
Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by loss of normal atonia during REM sleep, such that patients appear to act out their dreams.
Gagnon, Jean-Francois, Montplaisir, Jacques Y., Postuma, Ronald B.   +2 more
core   +4 more sources

Increased Corticomuscular Coherence in Idiopathic REM Sleep Behavior Disorder [PDF]

Frontiers in Neurology, 2011
The authors hypothesized that if locomotor drive increases along with rapid eye movement (REM) sleep without atonia in idiopathic REM sleep behavior disorder (RBD), then RBD patients would have greater corticomuscular coherence (CMC) values during REM ...
Chang-Hwan eIm, Deokwon eKo, Deokwon eKo, Heon-Jeong eLee, Ho-Kyoung eYoon, Hung Youl eSeok, Jae-Hyun eCho, Jae-Hyun eCho, Ki-Young eJung, Leen eKim   +9 more
core   +5 more sources

Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity [PDF]

Neuropsychiatric Disease and Treatment, 2015
Background: There are few studies describing periodic limb movement syndrome (PLMS) in rapid eye movement (REM) sleep in patients with narcolepsy, restless legs syndrome, REM sleep behavior disorder, and spinal cord injury, and to a lesser extent, in ...
Gaede, G., Paul, F., Radbruch, H., Sieb, J.P., Veauthier, C., Wernecke, K.D.   +5 more
core   +3 more sources

Screening Methods for REM Sleep Behavior Disorder [PDF]

, 2012
Keisuke Suzuki, Koichi Hirata, Masaoki Iwanami, Masayuki Miyamoto, Tomoyuki Miyamoto   +4 more
core   +3 more sources