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The objective of this article is to provide a comprehensive personal survey of all the major parasomnias with coverage of their clinical presentation, investigation, physiopathogenesis and treatment.
Roger J. Broughton
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Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by disrupting motor enactments during REM sleep, but also cognitive impairments across several domains.
Amandine Valomon +7 more
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Altered serotonergic neurotransmission may contribute to the non-motor features commonly associated with Parkinson’s disease (PD) such as sleep disorders. The 5-hydroxytryptophan (5-HTP) is the intermediate metabolite of l-tryptophan in the production of
M. Meloni +7 more
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Parkinson disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy are synucleinopathies, characterized by neuronal loss, gliosis and the abnormal deposition of α-synuclein in vulnerable areas of the nervous system.
A. Stefani +12 more
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REM sleep behavior disorder in Parkinson’s disease
Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disorder characterized by loss of normal muscle atonia during REM sleep with recurrent dream enactment and excessive motor activity. It is a frequent feature in patients with Parkinson's disease (PD) and other alpha-synucleinopathies, and can occur at any stage of the disease.
Muntean, Maria-Lucia +2 more
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Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is characterized by loss of the normal atonia of REM sleep accompanied by repetitive motor and behavior phenomena of dream content.
Kezban Aslan-Kara +19 more
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REM behavior disorder associated with sleep disordered breathing
REM behavior disorder (RBD) is a parasomnia characterized by muscle tonus during REM sleep and presence of vigorous movements which can be potentially harmful.
Maria Isabel Montes +3 more
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Impaired glycinergic transmission in hyperekplexia: a model of parasomnia overlap disorder
We report sleep phenotypes and polysomnographic findings in two siblings with a novel homozygous variant of the GLRA1 gene causing hereditary hyperekplexia (HH).
Régis Lopez +3 more
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The spectrum of disorders causing violence during sleep
Violent behavior during sleep is a common problem, affecting > 2% of the population > 15 years old as found in two large epidemiologic studies. The differential diagnosis of sleep related injury and violence includes: REM sleep behavior disorder (RBD ...
Carlos H. Schenck
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Long Sun,1,2 Keqing Li,3 Lili Zhang,3 Yunshu Zhang3 1Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 2National Health Commission of ...
Sun L, Li K, Zhang L, Zhang Y
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