Results 61 to 70 of about 19,197 (284)

Disorder-specific alterations of transient oscillatory dynamics during sleep across cortical and subcortical networks

Scientific Reports
Transient sleep oscillations reflect the dynamic coordination of cortical and subcortical circuits, modulated by slow oscillatory activity. However, the disorder-specific signatures of these events across neurological, pain, and sleep disorders remain ...
Nazanin Biabani, Katarina Ilic, Adam Birdseye, Olga Ivanenko, Sean Higgins, Jan Rosenzweig, Zoran Cvetkovic, Alexander D. Nesbitt, Carlotta Mutti, Liborio Parrino, Sharon Naismith, Panagis Drakatos, Karl Morten, David O’Regan, Peter J. Goadsby, Robert Leech, Ivana Rosenzweig   +16 more
doaj   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

Arthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source

Diagnostic tools for REM sleep behavior disorder [PDF]

Sleep Medicine Reviews, 2012
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by loss of muscle atonia during REM sleep that results in motor behaviors. Diagnosis of RBD involves a clinical interview in which history of dream enactment behaviors is elicited and a subsequent overnight polysomnography (PSG) evaluation to assess for REM sleep ...
Ariel B, Neikrug, Sonia, Ancoli-Israel
openaire   +2 more sources

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

Risk of Neurodegeneration in Patients with Rapid Eye Movement Sleep Behavior Disorder

Journal of Parkinson’s Disease, 2022
I discussed the risk of phenoconversions from idiopathic/isolated REM sleep behavior disorder (iRBD). Comorbidity with iRBD, such as obstructive sleep apnea, may accerelate the risk of α-synuclein-related neurodegenerative diseases.
Tomoyuki Kawada
doaj   +1 more source

Melatonin therapy for REM sleep behavior disorder [PDF]

Psychiatry and Clinical Neurosciences, 2001
AbstractRapid eye movement sleep behavior disorder (RBD) is a parasomnia with clinical symptoms that include punching, kicking, yelling and leaping out of bed in sleep. Polysomnographic (PSG) finding showed REM sleep without muscle atonia. Clonazepam is generally used for treating RBD symptoms but melatonin was reported to be effective so we ...
N, Takeuchi, N, Uchimura, Y, Hashizume, M, Mukai, Y, Etoh, K, Yamamoto, T, Kotorii, H, Ohshima, M, Ohshima, H, Maeda   +9 more
openaire   +2 more sources

Sleep‐trackers in the wild: A faceted taxonomy for information and interaction design

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Consumer‐grade sleep‐tracking technologies (CSTs) have brought sleep into everyday data practices, reframing it from a clinical concern into a site of personal optimization and reflection. Yet existing taxonomies of sleep‐tracking often medicalize users and overlook the complexity of sleep‐tracking technologies. This paper presents SleepTax, a
Sanonda Datta Gupta, Jaime Snyder, John S. Seberger   +2 more
wiley   +1 more source

Brainstem and spinal cord circuitry regulating REM sleep and muscle atonia. [PDF]

PLoS ONE, 2011
Previous work has suggested, but not demonstrated directly, a critical role for both glutamatergic and GABAergic neurons of the pontine tegmentum in the regulation of rapid eye movement (REM) sleep.To determine the in vivo roles of these fast-acting ...
Martina Krenzer, Christelle Anaclet, Ramalingam Vetrivelan, Nishang Wang, Linh Vong, Bradford B Lowell, Patrick M Fuller, Jun Lu   +7 more
doaj   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source