Results 81 to 90 of about 42,113 (336)
Epileptic Disorders, EarlyView.Abstract Objective Hypsarrhythmia is the classical EEG pattern of children with infantile epileptic spasms syndrome (IESS). Multifocal spikes, slow waves of large amplitude, and chaoticity are its main characteristics, but these lack clear definitions, and the interrater reliability (IRR) is poor.
T. P. Cramer +4 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing +4 more
wiley +1 more source
Parkinson's Disease, 2010 Pantothenate kinase-associated neurodegeneration (PKAN) is a familial or sporadic disease characterized by extrapyramidal and corticospinal signs with dementia. Patients show iron accumulation in the basal ganglia, with neuronal loss and gliosis.
Maria Livia Fantini +8 more
doaj +1 more source
Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain
Epilepsia, EarlyView.Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley +1 more source
Clocks & Sleep(1) Background: Phasic events in rapid eye movement (REM) sleep are a core feature of isolated REM behavior disorder (iRBD), which is often associated with emotion dysregulation.
Caterina Leitner +5 more
doaj +1 more source
Differential impact on isolated REM sleep without atonia by varying antidepressant therapies
Journal of Affective Disorders Reports, 2020 Background: REM sleep without atonia (RSWA) is characterized by increased phasic or tonic muscle activity in electromyography channels during polysomnography and usually causes REM sleep behavior disorder, but RSWA also exists within healthy populations ...
John Feemster +2 more
doaj +1 more source
Effects Of 4-thiazolidinone Derivatives Les-2658 And Les-1205 On Sleep - Wakefulness Cycle In Kindled Rats [PDF]
, 2017 The research is dedicated to in-depth study of neurotrophic and antiepileptic properties of original potential anticonvulsant agents from 4-thiazolidinones – LES-2658 (5-(3-nitro-benzylidene)-2-(thiazol-2-ylimino)-thiazolidin-4-one) and LES-1205 ([2,4 ...
Lesyk, R. (Roman) +2 more
core +2 more sources
An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition
Epilepsia, EarlyView.Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha +13 more
wiley +1 more source
A crime case which took place during REM sleep disorder and the evaluation of the case by the forensic psychiatry [PDF]
Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011 Sleep-related behavior disorders are the disturbing behaviors which occur during sleep, targeting himself or others. Although the exact prevalence is still unknown, it is clear that they are more frequent in males than females and mostly appear to be a ...
Sefa Saygili +3 more
doaj
Sleep disturbance at pre-deployment is a significant predictor of post-deployment re-experiencing symptoms. [PDF]
, 2019 Background: Insomnia is common in service members and associated with many mental and physical health problems. Recently, longitudinal data have been used to assess the impact of disturbed sleep on mental health outcomes.
Acheson, Dean T +8 more
core