Results 101 to 110 of about 19,197 (284)
Abstract Background Neuroinflammation, measured using [11C](R)‐PK11195 positron emission tomography (PET), has been reported in isolated rapid‐eye‐movement sleep behavior disorder (iRBD), but its temporal progression is unknown. Objective The aim was to assess longitudinal progression of neuroinflammation in iRBD patients and its relationship with ...
Andreas Myhre Baun +17 more
wiley +1 more source
Abstract Background [18F]Fluorodeoxyglucose positron emission tomography ([18F]FDG PET) represents an endorsed neurodegeneration biomarker in neuronal α‐synucleinopathies. Idiopathic/isolated rapid eye movement (REM) sleep behavior disorder (iRBD) represents a prodromal stage of such disorders.
Beatrice Orso +15 more
wiley +1 more source
Research has suggested that a bi-directional relationship exists between sleep disruption and depression. Not only is poor sleep a commonly reported symptom in those with depression, some aspects of sleep have also been shown to predict the onset of ...
Kita, Lauren Elizabeth
core
Characterization of autonomic dysfunction and sleep structure in REM sleep behavior disorder
LAUREA MAGISTRALEIl disturbo comportamentale del sonno REM (REM Sleep Behavior Disorder, RBD) è stato descritto per la prima volta nel 1986, ed è stato in seguito definito dall'American Academy of Sleep Medicine come una parasomnia caratterizzata dalla
MANDAS, NICLA
core
Abstract Background An accurate understanding of prognosis in Parkinson's disease (PD) is important for patient information provision, personalized treatment, and clinical trial design, but most previous research has been biased towards younger, healthier patients.
Angus D. Macleod +72 more
wiley +1 more source
Rapid Eye Movement Sleep Detection: A Machine Learning Approach Using Vital Signs
Rapid eye movement sleep (REM) is a critical sleep stage associated with several sleep disorders, including sleep apnea and rapid eye movement sleep behavior disorder.
Tzu-I. Tseng +2 more
doaj +1 more source
Peripheral Blood Inflammatory Cytokines in Idiopathic REM Sleep Behavior Disorder
BACKGROUND: Although previous research provides insight into the role of neuroinflammation in idiopathic REM sleep behavior disorder, the association of this disorder with peripheral blood inflammatory markers remains unclear.
Yong‐Won Shin +21 more
core +1 more source
The Global Parkinson's Disease Genetics (GP2) Genome Browser
Abstract Background Large‐scale sequencing initiatives have generated extensive genomic resources essential for variant interpretation, yet their effective use often requires bioinformatics expertise. To support identification of Parkinson's disease (PD) risk and disease‐causing variants, we developed an open‐access, summary‐level genomic data browser.
Zih‐Hua Fang +15 more
wiley +1 more source
LRRK2-Parkinson Disease patients with associated REM sleep behavior disorder.
LEDD: L-Dopa Equivalent daily dose; M+AT: polysomnographic montage quantifying "any" (tonic or phasic) type of EMG activity in the mentalis muscle plus bilateral anterior tibialis phasic EMG activity in REM sleep, using 3-sec mini-epochs (the cut-off for
Manel Salamero (720269) +18 more
core +1 more source
Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer +15 more
wiley +1 more source

