Results 91 to 100 of about 42,113 (336)

Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]

open access: yes, 2018
Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco   +3 more
core   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Motor–Behavioral Phenotypes in the RBD-PD Continuum: Neurophysiological Mechanisms and Rehabilitative Implications

open access: yesApplied Sciences
REM sleep behavior disorder (RBD) represents a prodromal manifestation of Parkinson’s disease (PD), reflecting the breakdown of inhibitory networks extending from the brainstem to the cortex.
Jae Woo Chung   +2 more
doaj   +1 more source

REM sleep behavior disorder in Parkinson’s disease

open access: yesJournal of Neural Transmission, 2014
Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disorder characterized by loss of normal muscle atonia during REM sleep with recurrent dream enactment and excessive motor activity. It is a frequent feature in patients with Parkinson's disease (PD) and other alpha-synucleinopathies, and can occur at any stage of the disease.
Muntean, Maria-Lucia   +2 more
openaire   +3 more sources

Sleep Disturbances and Phenoconversion in Patients with REM Sleep Behavior Disorder [PDF]

open access: gold, 2021
Hyunjin Jo   +4 more
openalex   +1 more source

Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future

open access: yesEpilepsia Open, EarlyView.
Abstract Electroencephalography (EEG) has evolved into an indispensable tool in pediatric epilepsy, fundamentally transforming the diagnosis, classification, and management of this condition. This review chronicles the historical journey of EEG from its groundbreaking inception to its current pivotal role in delineating distinct pediatric epilepsy ...
Hiroki Nariai
wiley   +1 more source

Polysomnographic Features of Sleep Disturbances and REM Sleep Behavior Disorder in the Unilateral 6-OHDA Lesioned Hemiparkinsonian Rat

open access: yesParkinson's Disease, 2014
Sleep pattern disruption, specifically REM sleep behavior disorder (RBD), is a major nonmotor cause of disability in PD. Understanding the pathophysiology of these sleep pattern disturbances is critical to find effective treatments.
Quynh Vo   +4 more
doaj   +1 more source

Exposure of Healthy Individuals to Pleasant Odours During Sleep: Effects on Odour Identification and Sleep Quality

open access: yesFlavour and Fragrance Journal, EarlyView.
Sleeping with pleasant odours was associated with improved cued odour identification, particularly in the sandalwood group. Subjective night‐time awakenings showed a descriptive decrease. EEG data did not reveal robust changes in sleep architecture, though exploratory analyses suggested potential benefits for individuals with poorer baseline sleep ...
Zetian Li   +4 more
wiley   +1 more source

Pinpointing brainstem mechanisms responsible for autonomic dysfunction in Rett syndrome:therapeutic perspectives for 5-HT1A agonists [PDF]

open access: yes, 2014
Rett syndrome is a neurological disorder caused by loss of function of methyl-CpG-binding protein 2 (MeCP2). Reduced function of this ubiquitous transcriptional regulator has a devastating effect on the central nervous system.
Abdala, Ana Paula   +2 more
core   +3 more sources

Evaluating Sleep Apnea: In‐Lab Versus at‐Home Recording Time and the Impact of Positional Disease

open access: yesThe Laryngoscope, EarlyView.
We evaluated the minimum recording time needed for in‐lab polysomnography (PSG1) and home sleep apnea test Type 3 portable monitoring (HSAT) to accurately reflect the full‐night apnea–hypopnea index (AHI) in patients with suspected obstructive sleep apnea (OSA).
Raquel Chartuni Pereira Teixeira   +1 more
wiley   +1 more source

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