Results 51 to 60 of about 19,197 (284)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Research Progress on Drug-related Rapid Eye Movement Sleep Behavior Disorder [PDF]

Zhongguo quanke yixue
Rapid eye movement sleep behavior disorder (RBD) is a parasomnia characterized by the loss of muscle atonia and the enactment of dreams during REM sleep, which can significantly impact the quality of life for both patients and their bed partners. RBD can
WANG Yi, CHENG Jinxiang, ZHAO Xianchao, REN Jiafeng, ZHANG Liping, DONG Menglong, LIN Zhifeng, SU Changjun
doaj   +1 more source

Antidepressants and their effect on sleep

, 2005
Given the relationship between sleep and depression, there is inevitably going to be an effect of antidepressants on sleep. Current evidence suggests that this effect depends on the class of antidepressant used and the dosage.
Mayers, Andrew G., Baldwin, David S., Mayers, A.G., Baldwin, D.S.   +3 more
core   +1 more source

FDG PET, dopamine transporter SPECT, and olfaction: Combining biomarkers in REM sleep behavior disorder [PDF]

, 2017
BACKGROUND: Idiopathic REM sleep behavior disorder is a prodromal stage of Parkinson's disease and dementia with Lewy bodies. Hyposmia, reduced dopamine transporter binding, and expression of the brain metabolic PD-related pattern were each associated ...
Adriaanse, Sofie M, Fransje E. Reesink, Teune, Laura K., Renken, Remco J, Sebastiaan Overeem, Sittig-Wiegand, Elisabeth, Heinen, Lisette, Mayer, Geert, Sofie M. Adriaanse, Meles, Sanne K., Lisette Heinen, Mayer, G Geert, Teune, Laura K, Jan Booij, Reesink, Fransje E., Laar, Teus van, Oertel, Wolfgang H., Overeem, S Sebastiaan, Depboylu, Candan, Luster, Marcus, Booij, Jan, Meles, Sanne K, Overeem, Sebastiaan, Renken, Remco J; id_orcid, Vadasz, David, Adriaanse, Sofie M., Renken, Remco J., Oertel, Wolfgang H, Kathrin Reetz, Teus van Laar, Sanne K. Meles, Laura K. Teune, Klaus L. Leenders, Reesink, Fransje E, Pijpers, Angelique, Elisabeth Sittig-Wiegand, Wolfgang H. Oertel, van Laar, Teus, Sittig-Wiegand, E., Leenders, Klaus L., Karl Kesper, Meles, Sanne K; id_orcid, Kesper, Karl, Overeem, Sebastiaan; id_orcid, Reetz, Kathrin, Remco J. Renken, Candan Depboylu, Angelique Pijpers, Helmut Höffken, Höffken, Helmut, Leenders, Klaus L, Marcus Luster, David Vadasz, Geert Mayer   +53 more
core   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Cyclic alternating pattern analysis in REM sleep behavior disorder

, 2013
Rapid eye movement (REM) sleep behavior disorder (RBD) is a type of REM parasomnia characterized by complex motor activity during REM sleep. In this study, cyclic alternating pattern (CAP) in patients with idiopathic RBD was analyzed to evaluate the ...
Benbir, Gülçin, Iseri, Pervin, Selekler, Macit, Karadeniz, Derya, KUTLU, AYŞE   +4 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Considering REM Sleep Behavior Disorder in the Management of Parkinson’s Disease

, 2023
Michela Figorilli,1 Mario Meloni,2 Giuseppe Lanza,3,4 Elisa Casaglia,1 Rosamaria Lecca,1 Francesca Lea Saibene,2 Patrizia Congiu,1 Monica Puligheddu1 1Sleep Disorder Research Center, Department of Medical Sciences and Public Health, University of ...
Saibene FL, Lanza G, Puligheddu M, Congiu P, Meloni M, Casaglia E, Lecca R, Figorilli M   +7 more
core  

REM sleep behavior disorder with predominant nightmares in a patient with ischemic pontine lesions

, 2022
REM sleep behavior disorder (RBD) is a parasomnia typically associated with synucleinopathy and evolving to neurodegenerative disorders. RBD is caused by impairment of brainstem nuclei controlling REM sleep muscle atonia.
Montini A., Vandi, Stefano, Pizza, Fabio, Plazzi G., Biscarini, Francesco, Plazzi, Giuseppe, Antelmi E., Vandi S., Montini, Angelica, Antelmi, Elena, Biscarini F., Pizza F.   +11 more
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source