Results 111 to 120 of about 9,602,001 (284)

Remaining useful tool life predictions in turning using Bayesian inference [PDF]

International Journal of Prognostics and Health Management, 2013
Tool wear is an important factor in determining machining productivity. In this paper, tool wear is characterized by remaining useful tool life in a turning operation and is predicted using spindle power and a random sample path method of Bayesian ...
Jaydeep M. Karandikar, Ali Abbas, Tony L. Schmitz   +2 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simplified modeling approach for predicting the remaining useful life of EV batteries in second-life applications

Future Batteries
An accurate assessment of the Remaining Useful Life (RUL) of battery modules is crucial for the technical and economic feasibility of repurposing electric vehicle (EV) batteries for second-life applications.
Maxime Montaru, Loïc Lonardoni, Lionel Serra, Nicolas Guillet   +3 more
doaj   +1 more source

Approach for remaining useful life prediction for mechanical equipment based on similarity

, 2016
In view of problem that remaining useful life of complex machinical equipment was difficult to predict, an approach for remaining useful life prediction based on similarity was presented.
YANG Jiankang, WU Bin, LI Hongwei, QU Bingni, LI Lu, SONG Jiancheng   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Data-driven remaining useful life prognosis techniques: stochastic models, methods and applications

, 2017
This book introduces data-driven remaining useful life prognosis techniques, and shows how to utilize the condition monitoring data to predict the remaining useful life of stochastic degrading systems and to schedule maintenance and logistics plans.
Si, Xiao-Sheng, Hu, Chang-Hua, Zhang, Zheng-Xin   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

INVESTIGATION OF REMAINING USEFUL LIFE OF GAS TURBINE BLADE [PDF]

, 2015
The aim of this research is to investigate the remaining useful life of gas turbine blade. This investigation was done by predicting the turbine blades service life using Stress Rupture Test (SRT) under accelerated test conditions where the applied ...
Osman, Muhammad Hafizuddin
core