Results 101 to 110 of about 10,687,564 (278)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

AI-powered fault diagnosis and estimation of remaining useful life using IoT framework

open access: yesDiscover Internet of Things
Unexpected malfunctions in industrial rotating machinery frequently result in decreased output and higher operating expenses. To achieve real-time anomaly identification and remaining useful life estimation, this work presents a novel predictive ...
Devdutt Patel   +2 more
doaj   +1 more source

Lubrication Oil Condition Monitoring and Remaining Useful Life Prediction With Particle Filtering [PDF]

open access: yesInternational Journal of Prognostics and Health Management, 2013
In order to reduce the costs of wind energy, it is necessary to improve the wind turbine availability and reduce the operational and maintenance costs.
Yongzhi Qu   +4 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

5G Architectures Enabling Remaining Useful Life Estimation for Industrial IoT: A Holistic Study

open access: yesIEEE Open Journal of the Communications Society
In the ever-evolving landscape of industrial connectivity, significant strides have been made in the integration of 5th generation (5G) cellular technology with Industrial Internet of Things (IIoT) systems.
Nicolo Longhi   +4 more
doaj   +1 more source

Remaining Useful Life Estimation by Image Recognition

open access: yes, 2021
Many methods for estimating remaining useful life (RUL) for predictive maintenance rely on sensor data. In environments where sensors might be economically unviable the condition of a machine or its parts is often assessed visually.
Probst, Thomas
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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