Results 51 to 60 of about 3,281,484 (268)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
IEEE Access, 2019 Lithium-ion batteries are the main form of energy providers for electric vehicles. To ensure the reliability and the safety of electric vehicles, it is necessary to estimate the remaining useful life of lithium-ion batteries.
Dongxu Shen +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Robust prediction of remaining useful lifetime of bearings using deep learning
Engineering Applications of Artificial Intelligencehis research has been partially funded by the Spanish National Plan of Research, Development and Innovation under the project EDNA (PID2021-124383OB-I00) and the University of Oviedo, Spain. L. Magadán is supported by the Severo Ochoa program (PA-22-BP21-120).
Luis Magadán +2 more
openaire +2 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Meteorologische Zeitschrift, 2023 Due to technical progress in sensor technology and computer power, observation and model data are operationally available today with a high spatial and temporal resolution, suitable for thunderstorm detection and prediction.
Isabella Zöbisch +2 more
doaj +1 more source
Propulsion and Power Research, 2021 The in-service life of turbine blades directly affects the on-wing lifetime and operating cost of aircraft engines. It would be essential to accurately evaluate the remaining useful life of turbine blades for safe engine operation and reasonable ...
He Liu +3 more
doaj +1 more source