Results 71 to 80 of about 3,281,484 (268)

Assessment of Early Stopping through Statistical Health Prognostic Models for Empirical RUL Estimation in Wind Turbine Main Bearing Failure Monitoring

Energies, 2019
Details about a fault’s progression, including the remaining-useful-lifetime (RUL), are key features in monitoring, industrial operation and maintenance (O&M) planning. In order to avoid increases in O&M costs through subjective human involvement
Jürgen Herp, Niels L. Pedersen, Esmaeil S. Nadimi   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Real Behaviour and Remaining Lifetime of Bridge Structures

, 2008
The paper presents results of research activities of the Department of Structures and Bridges in the field of investigation of the real behaviour, reliability and durability of existing bridge structures.
Josef Vican, Patrik Kotula, Jozef Gocal, Branislav Melis, Peter Kotes   +4 more
core   +1 more source

Effect of short-circuit degradation on the remaining useful lifetime of SiC MOSFETs and its failure analysis [PDF]

, 2020
When the SiC MOSFET works in the normal operating conditions, its remaining useful lifetime used to be estimated based on the monitored parameters and the lifetime model derived from accelerated tests.
Letz, Sebastian, Goetz, Thomas, Schletz, Andreas, Du, He, Iannuzzo, Francesco; id_orcid, Baker, Nick   +5 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Estimation of the remaining useful life of hydro generators [PDF]

, 2021
O monitoramento da condição dos geradores é muito desejável para uma operação confiável de uma usina hidrelétrica. As atividades de manutenção podem ser programadas para evitar falhas inesperadas que podem levar a meses ou anos de máquinas paradas sem ...
BERNARDES JUNIOR, José Vitor
core   +1 more source

A Novel Hybrid Transformer for RUL Prediction in Predictive Maintenance for Smart Manufacturing

EAI Endorsed Transactions on Industrial Networks and Intelligent Systems
Ensuring continuous operation and minimizing unexpected failures are critical priorities in industrial manufacturing. Due to this requirement, smart manufacturing has transformed maintenance strategies, moving from traditional scheduled approaches to ...
Huu Du Nguyen, Xuan Hoang Nguyen, Bich Thuong Dao, Cong Ngon Do, Thu Huong Truong   +4 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Machine performance degradation assessment and remaining useful life prediction using proportional hazard model and SVM [PDF]

This paper proposes a three-stage method involved system identification techniques, proportional hazard model, and support vector machine for assessing the machine health degradation and forecasting the machine remaining useful life (RUL).
Tran, Van Tung
core   +3 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source